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Fundraiser by Lifespan.io & CellAge: Targeting Senescent Cells With Synthetic Biology

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Categories: Announcements, Science, Transhumanism, Tags: , , , , , , , , , , , , ,

The New Renaissance HatCellAge
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Editor’s Note: The Rational Argumentator and the U.S. Transhumanist Party support Lifespan.io and CellAge in their work towards groundbreaking scientific life-extension research. Finding a way to repair age-related damage to senescent cells would be a fundamental breakthrough for transhumanism, and we offer our best wishes and support for those striving towards these new technologies.

               ~ Gennady Stolyarov II, Editor-in-Chief, The Rational Argumentator, December 11, 2016

From Lifespan.io and CellAge:

Our society has never aged more rapidly – one of the most visible symptoms of the changing demographics is the exponential increase in the incidence of age-related diseases, including cancer, cardiovascular diseases and osteoarthritis. Not only does aging have a negative effect on the quality of life among the elderly but it also causes a significant financial strain on both private and public sectors. As the proportion of older people is increasing so is health care spending. According to a WHO analysis, the annual number of new cancer cases is projected to rise to 17 million by 2020, and reach 27 million by 2030. Similar trends are clearly visible in other age-related diseases such as cardiovascular disease. Few effective treatments addressing these challenges are currently available and most of them focus on a single disease rather than adopting a more holistic approach to aging.

Recently a new approach which has the potential of significantly alleviating these problems has been validated by a number of in vivo and in vitro studies. It has been demonstrated that senescent cells (cells which have ceased to replicate due to stress or replicative capacity exhaustion) are linked to many age-related diseases. Furthermore, removing senescent cells from mice has been recently shown to drastically increase mouse healthspan (a period of life free of serious diseases).

Here at CellAge we are working hard to help translate these findings into humans!

CellAge, together with a leading synthetic biology partner, Synpromics, are poised to develop a technology allowing for the identification and removal of harmful senescent cells. Our breakthrough technology will benefit both the scientific community and the general public.

In short, CellAge is going to develop synthetic promoters which are specific to senescent cells, as promoters that are currently being used to track senescent cells are simply not good enough to be used in therapies. The most prominently used p16 gene promoter has a number of limitations, for example. First, it is involved in cell cycle regulation, which poses a danger in targeting cells which are not diving but not senescent either, such as quiescent stem cells. Second, organism-wide administration of gene therapy might at present be too dangerous. This means senescent cells only in specific organs might need to be targeted and p16 promoter does not provide this level of specificity. Third, the p16 promoter is not active in all senescent cells. Thus, after therapies utilizing this promoter, a proportion of senescent cells would still remain. Moreover, the p16 promoter is relatively large (2.1kb), making it difficult to incorporate in present gene therapy vehicles. Lastly, to achieve the intended therapeutic effect the strength of p16 promoter to drive therapeutic effect might not be high enough.

CellAge will be constructing a synthetic promoter which has a potential to overcome all of the mentioned limitations. A number of gene therapy companies, including uniQure, AGTC and Avalanche Biotech have successfully targeted other types of cells using this technology. With your help, we will be able to use same technology to develop tools and therapies for accurate senescent cell targeting.

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G. Stolyarov II Interviews Demian Zivkovic Regarding the D.N.A. – Gene Therapies Congress

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Categories: Announcements, Science, Transhumanism, Tags: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

The New Renaissance Hat
G. Stolyarov II and Demian Zivkovic
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Mr. Stolyarov invited Demian Zivkovic, President of the Institute of Exponential Sciences (IES), to discuss the forthcoming Designing New Advances (D.N.A.) Gene Therapies Congress in Utrecht, The Netherlands.

The interview took place on Sunday, June 19, 2016, at 11 a.m. US Pacific Time. Watch the recording here.

The D.N.A. Congress is scheduled to occur on July 9, 2016, and will feature speakers such as Oliver Medvedik, Aubrey de Grey, Elizabeth Parrish, Keith Comito, and Tatjana Kochetkova. This event receives the strong endorsement of both The Rational Argumentator and the Nevada Transhumanist Party.

Read the announcement of the D. N. A. Congress here.

Contribute to the fundraiser for the D. N. A. Congress on Indiegogo  and Generosity.

DNA_Interview_CoverDemian Zivkovic is the president of the Institute of Exponential Sciences  (Facebook  / Meetup) – an international transhumanist think tank / education institute comprised of a group of transhumanism-oriented scientists, professionals, students, journalists, and entrepreneurs interested in the interdisciplinary approach to advancing exponential technologies and promoting techno-positive thought. He is also an entrepreneur and student of artificial intelligence and innovation sciences and management at the University of Utrecht.

Demian and the IES have been involved in several endeavors, such as organizing lectures on exponential sciences, interviewing experts such as Aubrey de Grey, joining several of Mr. Stolyarov’s futurism panels, and spreading Death is Wrong – Mr. Stolyarov’s illustrated children’s book on indefinite life extension – in The Netherlands.

Demian Zivkovic is a strong proponent of healthy life extension and cognitive augmentation. His interests include hyperreality, morphological freedom advocacy, postgenderism, and hypermodernism. He is currently working on his ambition of raising enough capital to make a real difference in life extension and transhumanist thought.

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Major Mouse Testing Program Crowdfunding Campaign Announcement by International Longevity Alliance

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Categories: Announcements, Science, Transhumanism, Tags: , , , , , , , , , , , , , , , ,

The New Renaissance HatInternational Longevity Alliance

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Editor’s Note: The Rational Argumentator strongly supports the Major Mouse Testing Project crowdfunding campaign, and I have personally pledged $100 to this effort. Furthermore, I am honored that copies of my illustrated children’s book Death is Wrong are being made available as rewards for certain tiers of contributors to this research fundraiser.

~ Gennady Stolyarov II, Editor-in-Chief, The Rational Argumentator, May 11, 2016

The International Longevity Alliance is conducting a crowdfunding campaign to support the investigation of senolytic drugs’ potential to extend life. The team is going to study the combination of three senolytic drugs – Dasatinib, Venetoclax, and Quercetin – in mice, to see if the removal of senescent cells can ensure extended maximum lifespan. With highly devoted scientists and volunteers working for MMTP, the project needs only $60,000 to begin this experiment, as the researchers would need only to buy the mice and pay for their housing, the substances to test, and the battery of tests to analyze health changes.

Will you help to fund this research? Then please go to Lifespan.io, and choose the donation that suits you best and receive the deepest gratitude of the team and a nice useful souvenir to remember your input into the investigation of longevity therapies!

MMTP_Project1_StairFind out more about the International Longevity Alliance here.

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The 2014 Fight Aging! Fundraiser Starts Now: We’ll Match Your Research Donations with $2 for Every $1 Given – Article by Reason

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Categories: Science, Transhumanism, Tags: , , , , , , , , , , , ,

The New Renaissance Hat
Reason
October 4, 2014
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Note from the Editor: The Rational Argumentator strongly supports this matching fundraiser and encourages all readers to donate any sums of money to the SENS Research Foundation, in order to accelerate the basic research into and the development of cures for the debilitating diseases of old age. I personally made a donation of $100 on October 4, 2014, knowing that its impact will be tripled through a 2-for-1 additional contribution by the generous donors who established the matching fund. This is the time to leverage our resources and ensure that this literally vital research gets done as soon as possible. I am grateful to Reason of FightAging.org for his tireless efforts in advocating for life-extension research and spearheading campaigns to attract the funding that this area of science urgently needs.

~ Gennady Stolyarov II, Editor-in-Chief, The Rational Argumentator, October 4, 2014

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It is that time again, and our 2014 matching fundraiser started October 1st 2014. From now until the end of the year, December 31st 2014, we will match the first $50,000 donated to the SENS Research Foundation with $2 for every $1 given. These funds will help to speed progress in ongoing scientific programs conducted in US and European research centers, their ultimate aim being to repair and reverse the causes of frailty and age-related disease.

The SENS Research Foundation is a 501(c)(3) charity and all US donations are tax-deductible. Donations from most European Union countries are also tax-deductible, though the details vary by location. Please contact the SENS Research Foundation to find out more.

The Matching Fund Founders Ask You to Join Us

Who are we? We are Christophe and Dominique Cornuejols, David Gobel of the Methuselah Foundation, Dennis Towne, Håkon Karlsen, philanthropist Jason Hope, Michael Achey, Michael Cooper, and Reason of Fight Aging! We are all long-time supporters of SENS research aimed at rejuvenation through repair of the known root causes of aging. The few types of cellular and molecular damage that accumulate in all of our tissues cause progressive dysfunction and eventual death for everyone – unless something is done to stop it. This cause is important enough for everyone to do their part, and for us that means putting up a $100,000 matching fund we want you to help draw down: for every dollar you donate, we will match it with two of our own.

Even Small Donations Make a Meaningful Difference

Early stage medical biotechnology research of the sort carried out at the SENS Research Foundation costs little nowadays in comparison to the recent past. The cost of tools and techniques in biotechnology has plummeted in the past decade, even while capabilities have greatly increased. A graduate student with $20,000 can accomplish in a few months what would have required a full laboratory, years, and tens of millions of dollars in the 1990s. All of the much-lamented great expense in modern medicine lies in clinical translation, the long and drawn out process of trials, retrials, marketing, and manufacturing that is required to bring a laboratory proof of concept into clinics as a widely available therapy.

The SENS Research Foundation is focused on early stage research, following a plan that leads to technology demonstrations in the laboratory. With a proof of concept rejuvenation therapy the world will beat a path to their doorstep in order to fund clinical translation. The real challenge is here and now, raising the funds to get to that step. A few tens of thousands of dollars means the difference between a significant project delayed indefinitely or that project completed.

To pick one example, last year the community raised $20,000 to fund cutting edge work in allotopic expression of mitochondrial genes, a potential cure for the issue of mitochondrial damage in aging. That was enough to have a skilled young researcher work on the process for two of the thirteen genes of interest over a period of months. It really is that cheap given an existing group like the SENS Research Foundation with diverse connections and access to established laboratories.

Your donations make a real difference.

Spread the Word, Tell Your Friends

Don’t forget to tell your friends about this fundraiser. Talk to your community, online and offline. Consider running local events to help meet our goal of raising $50,000 from a grassroots community of supporters. The more people who know about the prospects for near future therapies resulting from rejuvenation research of the sort carried out by the SENS Research Foundation, the easier it becomes to raise funds and obtain institutional support for these research programs in the future.

Launched at /r/Futurology and in Conjunction with Longevity Day

Take a look at the generous spirit displayed at /r/Futurology, the futurist Reddit community, when given the chance to help. Scores of people there have already donated modest sums to the cause in response to our fundraiser: many thanks to you all!

The 1st of October marks the launch of this fundraiser, but it is also the International Day of Older Persons, and the International Longevity Alliance would like this to become an official Longevity Day. This year, just like last year, groups of futurists around the world will be holding events to mark the occasion, and this includes the scientists and advocates present at the 2014 Eurosymposium on Healthy Aging.

Download the 2014 Fundraiser Posters

The full size graphics here are large enough for 24 x 36 inch posters, but are also suitable for page-sized fliers. The original Photoshop files are available on request, but are a little large to put up here. Make as much use of these as you like – please help to spread the word and help this fundraiser to meet its target.

Color design, 3600 x 5600 pixels suitable for 24 x 36 inch posters, 11.3MB
Color design, 2400 x 3600 pixels suitable for letter size, 6.3MB

Blue design, 7200 x 10800 pixels suitable for 24 x 36 inch posters, 13.1MB
Blue design, 2400 x 3600 pixels suitable for letter size, 3.8MB

Reason is the founder of The Longevity Meme (now Fight Aging!). He saw the need for The Longevity Meme in late 2000, after spending a number of years searching for the most useful contribution he could make to the future of healthy life extension. When not advancing the Longevity Meme or Fight Aging!, Reason works as a technologist in a variety of industries. 
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This work is reproduced here in accord with a Creative Commons Attribution license. It was originally published on FightAging.org.

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MILE Activist Contest II Entry: Life-Extension Game Developers’ Matching Fund – Post by G. Stolyarov II

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Categories: Transhumanism, Tags: , , , , , , , , , , , , , , , , , , , ,

The New Renaissance Hat
Gennady Stolyarov II
August 18, 2014
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This is Mr. Stolyarov’s entry into the Movement for Indefinite Life Extension (MILE) Activist Contest II.

Computer games are a powerful way to spread the message of indefinite life extension to a new demographic. By engaging the players through art, concepts, and gameplay elements expressing the feasibility and desirability of indefinite lifespans, computer games can attract interest in life-extension activism that will be perceived as leisure and entertainment by those who engage in it.

If I had $5,000 to devote to raising awareness about people, projects, and organizations wording toward indefinite life extension, I would create a matching fund for fundraising projects pertaining to life-extension-themed computer games currently in development. This Life-Extension Game Developers’ Matching Fund (LEGDMF) would match, dollar for dollar, the funds raised via Indiegogo, Kickstarter, and other crowdfunding platforms by game developers whose works would meet the following criteria:

(i) The game should promote and express the message of indefinite life extension in a favorable way.

(ii) The game should enable the player to find out about some of the people, projects, and organizations working toward indefinite life extension.

(iii) An alpha, beta, or demo version of the game should exist and be playable by the general public.

(iv) The game developers must be willing to publicly disclose the amount of funds raised, either through a fundraising platform or through information they post directly on a publicly viewable website.

A great example of a life-extension-themed game, whose gameplay also deeply integrates the pursuit of longevity escape velocity, is LEV: The Game , which is currently in the midst of an Indiegogo fundraiser. (For more details, read my recent article about LEV: The Game.) LEV: The Game would be one of the efforts, but not necessarily the only effort, which could be greatly aided by the LEGDMF.

The purpose of a matching fund is to bring in additional resources by enabling any donor to leverage the impact of his or her contribution. Instead of selecting eligible games through a contest where a panel of judges or the contest organizer(s) would decide upon the winning entries, a matching fund enables donors from the general public to vote with their money and helps these votes to matter more in influencing real-world outcomes. The LEGDMF would continue to match contributions to eligible game-development projects, dollar for dollar, until the $5,000 fund is exhausted.

An advantageous feature of the LEGDMF would be that all the money could be given directly to eligible game-development projects. Fundraising platforms would collect fees ranging from 4% to 9% of the funds donated, and payment platforms – such as PayPal or payment processors employed by banks – would collect additional fees. However, it would be unlikely that the total fees would exceed 15% of the funds contributed, meaning that more than $4,250 (85% of $5,000) would substantively benefit game developers in their efforts to create engaging, immersive, and entertaining portrayals of the life-extension message.

Success for the LEGDMF would be measured by the ability to successfully fund the creation of a life-extension-themed game (or even multiple games) and, ultimately, by the release of such a game to the general public and the amount of engagement (number of plays or number of downloads) that the game would receive. A nearer-term measure of success would be the ability to attract sufficient interest in life-extension-themed games as to raise $5,000 in independent contributions from the general public, which would exhaust the LEGDMF through matching donations – leading to a total of $10,000 in funds invested in this worthwhile goal of informing new demographics about life extension through an exciting and innovative medium.

The demographics that could potentially be attracted by life-extension-themed computer games would include anybody who plays computer games for entertainment. Gamers come in all ages, but there are many children and teenagers among them, who could become vital members of the next generation of scientists, technologists, philosophers, and activists working in pursuit of indefinite longevity. These individuals would discover the life-extension-games once they are released on various online sites. Depending on the game, these could be flash-game sites that allow the games to be played for free, or these could be sites offering files for download. While no game can guarantee a specific number of players, games that are designed well and have an innovative premise would attract a large user base through the appeal of the gameplay itself. A game that catches on and achieves a steady following could even revolutionize the public perception of indefinite life extension and bring the idea of pursuit indefinite lifespans into the cultural mainstream.

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LEV: The Game – Play to Win Indefinite Life – Article by G. Stolyarov II

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Categories: Technology, Transhumanism, Tags: , , , , , , , , , , , , , ,

The New Renaissance Hat
G. Stolyarov II
July 20, 2014
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LEV: The Game is a work in progress, whose potential to spread the message of indefinite life extension to the general public encourages me greatly. Developed by a team from Belgium – consisting of Anthony Lamot, Mathieu Hinderyckx, and Maxime Devos – this Android mobile game is currently in its Alpha phase. The creators have initiated an Indiegogo fundraiser to raise 6000 Euros (approximately 8100 US dollars at July 2014 exchange rates) in order to greatly expand the game and add its most complex and engaging elements. You can watch their video introduction to the game and the fundraiser here.

The premise of LEV: The Game is the same as the aim of those of us who wish to extend our lives without end. One’s character is challenged with living for as long as possible and attaining longevity escape velocity by reversing the damage of senescence at a faster rate than it accumulates. Every year in the game, the character receives an allotment of energy points with which to purchase power-ups, such as stem-cell therapies, applications of nano-medicine, cybernetic enhancements, or simple increments of diet and exercise. Each power-up can either increase the remaining expected lifespan, increase the rate at which energy points accumulate (called “productivity” in the game), or reduce the character’s rate of bodily decay. The player needs to achieve a delicate balancing of these power-ups to avoid expiring before he/she accumulates enough energy points to purchase the next life-extending advance.

Becoming an Alpha tester of LEV: The Game is absolutely free, and I was pleased to be able to participate in mid-July 2014. After eight attempts, I succeeded in getting a character to reach the age of 200, which is the game’s current victory condition. If the developers can raise their desired funds, they anticipate extending the gameplay to enable one’s character to reach the age of 1000.

LEV_Maximus_VIII_ScreenshotTo become an Alpha tester, you will need to join the LEV: The Game (Alpha) Google Group, using a Google account that is also linked to a mobile phone or tablet that runs the Android operating system. After you join, you can download the game from the Google Play store here. Remember to click the “Become a Tester” button to enable the download to work. When testing the game in this early stage, make sure you un-pause it first using the speed settings in the top-left-hand portion of the screen, before navigating to any of the other available windows.

Why LEV: The Game is Immensely Important

Our ability to achieve indefinite life extension personally will depend on the amount of resources and support from the general public invested in the overcoming of age-related bodily damage. Most people, unfortunately, continue to either be resigned to the inevitability of death, or to argue against the desirability of indefinite longevity due to extremely basic misconceptions. Even apart from the absurdly false boredom argument, overpopulation argument, and “playing God” argument, there is a more basic fallacy – the Tithonus error, which posits that becoming chronologically older necessarily means becoming biologically more decrepit. Yet the only way indefinite longevity could be achieved would be for people to remain biologically young, so that their susceptibility to deadly diseases does not increase beyond that of people in their twenties today. How could longevity advocates get the general public to understand this? Convincing people through arguments alone may often fail, simply because the Dragon-Tyrant of death is so ubiquitous and so overwhelming that many people will grasp at any straw, no matter how flimsy, to avoid being confronted with the grave injustice of their current predicament.

But a game gives a fresh, different, and engaging way to see and experience what indefinite longevity would truly entail. Anyone playing LEV: The Game would quickly see that becoming increasingly frail is no way to increase life expectancy. Your character will die if he/she experiences sufficient biological decay. You will be able to see a graph of the character’s remaining life expectancy and the rate at which decay is expected to proceed during the years they have left. If you apply the most effective combinations of power-ups, you will also see the life-expectancy curve shift upward – sometimes slightly, at other times by massive jumps. The latter situation reflects what can happen once humans begin to undergo periodic rejuvenation therapies to remove age-related damage, as posited in Dr. Aubrey de Grey’s SENS approach.

Furthermore, LEV: The Game encourages its players to engage in paradigm-shifting thinking about their own future trajectories. Instead of planning for gradual debilitation and eventual death, as most people do today when projecting their careers, retirements, finances, and family lives, a strikingly different mindset can take hold – the quest for perpetual maintenance and a return to youthfulness that may be possible at any chronological age, with sufficient technological advances and vigilance regarding one’s health. I admire the integration in LEV: The Game of biomedical treatments, cybernetic enhancements, and simple prudent habits – such as a healthy diet, regular exercise, cognitive activity, and access to relevant health information (even “Quantified Self” is a power-up that one can purchase). We should all strive to live the most informed and healthy lives possible, given present technology, in order to maximize our chances of surviving to the next wave of breakthroughs on the way to longevity escape velocity.

Not a day passes when I do not think about innovative ways to reach the general public with the message of indefinite life extension. For years, I have advocated the gamification of this literally vital idea as one of the most powerful ways to catalyze cultural change on this issue. I am immensely pleased to now witness such an effort taking off, due to the excellent work of Messrs. Lamot, Hinderyckx, and Devos. I donated to the Indiegogo fundraiser to help propel LEV: The Game to its hopefully world-changing final version. I hope that all readers of this article will be able to do the same.

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Movement for Indefinite Life Extension Year Two Goal Advertisement Fundraiser – Article by Eric Schulke

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Categories: Announcements, Transhumanism, Tags: , , , , , , , , ,

The New Renaissance Hat
Eric Schulke
June 3, 2014
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We are collecting $100 pledges for this Movement for Indefinite Life Extension Year Two Goal Advertisement Fundraiser (MILE y2 Fund). At this time there is a total of $600 pledged. If you want to get in on this, then send us a message at the Movement for Indefinite Life Extension Facebook page. The deadline for making pledges is 20:00 CST, June 15th 2014. You can either have us place the ads for you by sending the money in via PayPal, or you can request to place your own, and we will set you up with the basics.

The Movement for Indefinite Life Extension, which is more like a group spirit that promotes everybody, rather than something like a Foundation or Corporation, is pushing a 5-year goal to inform 8 million people about the individuals, projects, and organizations that are working directly or indirectly toward the goal of indefinite life extension. It is executed in 5 progressive steps.

mile_year_2_goal_fund_movement_for_indefinite_life_extension_year_two_goal_july_17_2014_8000_likes_facebook_dot_com_slash_movement_for_indefinite_life_extensionYear One, which was completed on July 17th of last year, 2013, had the goal of reaching 800 “likes” in this awareness driving campaign.

We are now on our way to the Year Two goal of 8,000 “likes”, with the goal’s deadline coming up soon on July 17, 2014. We are right on schedule with saturation of organic likes and are confident that we can come in on time with the goal of 8,000, and probably exceed it, by the deadline, with around $1,000 in Facebook ads that are targeted to like-minded people and groups. (Of course, the more donations, the better. We’re all working to drive awareness to a critical mass of at least 8 million people for the final goal.)

Millions of people are hearing and learning about the work that is going on to make indefinite healthy life spans a reality, through all the press, events, projects, and endeavors that people around the world have been working on over the decades. With advertisements, we can find more of them and get them to consider putting their weight behind the general movements of transhumanism and indefinite life extension. The rate at which we grow to critical mass, and generate awareness, matters. The clock is ticking.

The important cause of life is the incentive. In addition to that, there is the small incentive that the group of people that pledges to this Movement for Indefinite Life Extension Year Two Goal Fundraiser, will be written about as instrumental leaders in the success of the Movement for Indefinite Life Extension Year Two Goal, and in the movement in general.

Eric Schulke was a director at LongeCity during 2009-2013. He has also been an activist with the Movement for Indefinite Life Extension and other causes for over 13 years.

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“Death is Wrong” – Book Distribution and Call to Action – May 28, 2014 – Video by G. Stolyarov II

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Categories: Announcements, Education, Transhumanism, Tags: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

Mr. Stolyarov provides an update regarding the effort to distribute over 1,000 free, paperback copies of Death is Wrong to children.

As of May 28, 2014, 644 books have been sent out, and 385 remain to be distributed, out of an eventual goal of 1,029 books provided to children, free of cost to them.

Instructions for Longevity Activists to Request Copies of “Death is Wrong”

– Send an e-mail to gennadystolyarovii@gmail.com

– Provide (i) your name, (ii) your mailing address, (iii) a statement of your support for indefinite life extension, and (iv) a brief description of your plan to spread the book to children in your local area. Remember that all copies received pursuant to this initiative would need to be offered to children free of charge (as gifts or reading opportunities) and may not be resold.

– Provide the number of copies of Death is Wrong that you are requesting.

– Preferably, provide an indication that you would be willing to send photographs of the books that have been delivered to you as well as events where you will be distributing the books.

References
Death is Wrong on Amazon:
* Paperback version
* Kindle version
Death is Wrong Official Home Page
– “Spreading the Word That Death is Wrong” – Article by Gennady Stolyarov II
Updates Regarding Book-Distribution Effort
– Death is Wrong Book Trailer – Video by Peter Caramico

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Eternal Life Fan Club Review of “Death is Wrong” – Article and Graphic by Roen Horn

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Categories: Art, Education, Tags: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

The New Renaissance Hat
Roen Horn
April 28, 2014
Recommend this page.
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This review was originally posted on the Facebook page of the Eternal Life Fan Club, a community created by Roen Horn to share philosophy, research, and strategies to help humans increase their chances of living forever.
ELFC_Death_is_Wrong

I finally got around to reading the new transhumanist children’s book Death is Wrong. I was impressed with the simplicity and clarity of the message, and my impression was that children could easily digest the information. It’s about time there was a children’s book promoting the message of indefinite life-extension. This book should be mandatory reading in elementary schools. I was pleased to see that the book gave mention to Aubrey de Grey and SENS Research Foundation. Besides explaining the logical reasons for why death is wrong, I was delighted that the book spoke about the frailness of life and the overwhelming sadness of death. The book also specified the importance of vigilantly avoiding dangerous behaviors which would endanger one’s life, and the importance of taking care of one’s health. I think that message is especially important for young children to hear. The book leaves the reader with the optimistic outlook that death does not have to be inevitable. If we know that death is wrong, then we must wage war on death and never give up until we have won this fight. You can find the book on Amazon here.

Wendy Stolyarov, Illustrator of "Death is Wrong", at the Transhuman Visions 2.0 Conference - March 1, 2014

Wendy Stolyarov, Illustrator of Death is Wrong, at the Transhuman Visions 2.0 Conference – March 1, 2014

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“Death is Wrong” Fundraiser: Another Ship Returns to Harbor after Braving the Seas for the Cause – Article by Eric Schulke

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Categories: Art, Education, Philosophy, Science, Technology, Transhumanism, Tags: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

The New Renaissance Hat
Eric Schulke
April 26, 2014
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On December 2nd of 2013, the Movement for Indefinite Life Extension began a contest for people to send in their ideas on how to spend money on outreach for the cause. The following question was asked:

If you were to receive a check in the mail with $5,000 to inform as many people as possible about the desirability and the prospects for indefinite life extension, to get them interested in the people, projects and organizations working directly or indirectly toward indefinite life extension, then how might you spend it?

Six entries were entered into a poll.

The entry with the most votes was Gennady Stolyarov’s entry to distribute 1,000 copies of his and his wife Wendy’s great new children’s book Death is Wrong. Their winning entry won them one of four books that were given away for the contest: a signed copy of The Transhumanist Wager, which was generously contributed to the project by its author, Zoltan Istvan.

A group of us put our heads together and came up with a plan to raise the money. The fundraiser was launched on February 23rd of 2014 and successfully completed on April 23rd of 2014.

It is a great success on multiple levels for the Death is Wrong book and vision in itself, which supports indefinite-life-extension research and philosophy in general, and which is written by one of the many Movement for Indefinite Life Extension leaders, Gennady Stolyarov.

It is also a great success for the Movement for Indefinite Life Extension in general on many levels. It is one of the first major projects the MILE has executed in its upcoming series of projects to work to reach 80,000 “likes” at MILE Facebook page for the Year 3 goal, which begins on July 17th 2014, and tasks us with collectively helping to achieve the group victory of moving from 8,000 likes, to 80,000 likes by the July 17th of the following year, 2015.

Rodney Ashby and Jason Shields helped us get the momentum rolling and did fundraising throughout, and Tonya Scholz gave the project a big hand. Gennady Stolyarov made an amazing media tour for the project, finding himself talking about it in interviews and getting mentions and reports from a variety of sources. Most of them are of his own arranging, some of these outlets picked the story up on their own, and there are some opportunities that I arranged. They include, but are not limited to, the following:

There were 92 contributions from over 80 individuals and one group, including, but not limited to:

There were also at least 13 anonymous donations. I did a count of all of the donors that I brought in. A close, conservative estimate is that I brought in around 70% of them.

We ended up raising $5,141, compounding on the success by $141. That means that we raised enough to distribute 29 more books than projected. Those of us that worked with this didn’t take a single dime as a cut of this. I put a hundred dollars or so in ads into it, and Wendy and Gennady have given countless hours of their time to rewarding donors. Countless others, like general activists and reporters, have put their time and resources into this. The Life Extension Foundation made an inspiring and generous $1,255 dollar donation to close the deal.

Gennady and I have already secured the distribution of 140 copies, and there are now over 1,000 total available for distribution. An order even went out to Aubrey de Grey, whose work is one of the many topics that is talked about in the book. Gennady Stolyarov writes in the Indiegogo update page that,

Update of April 16, 2014: I am delighted to announce that a shipment of 10 Death is Wrong books was made yesterday to Dr. Aubrey de Grey himself at the SENS Research Foundation. Since Dr. de Grey’s work is a crucial inspiration for Death is Wrong and my longevity activism more generally, I am immensely pleased that he has agreed to receive this shipment and make the books available for distribution.

We encourage the distribution of Death is Wrong books to places like schools, libraries, and directly to parents and children. We ask people to order as many copies as they think they may be able to give away to kids and people with kids, at Transhuman and health events, rallies, and similar events. Gennady has instructions on how to order them free of charge:

Instructions for Longevity Activists to Request Copies of Death is Wrong

– Send an e-mail to gennadystolyarovii@gmail.com

– Provide your name, your mailing address, a statement of your support for indefinite life extension, and a brief description of your plan to spread the book to children in your local area. Remember that all copies received pursuant to this initiative would need to be offered to children free of charge (as gifts or reading opportunities) and may not be resold.

– Provide the number of copies of Death is Wrong that you are requesting.

– Preferably, provide an indication that you would be willing to send photographs of the books that have been delivered to you as well as events where you will be distributing the books.

The project has been a great community effort. The Movement for Indefinite Life extension is our collective spirit, not an organization. Together we collect supporters for all of the constructive projects and organizations. There must have been over 150 people involved. More activists flexed their life-extension muscles, and we helped more people that want to get involved to take the first step. If you’ve ever saved money, then you know how incremental change adds up. You cannot achieve the saving of $8,000 unless you first get to $2,000, and $6,000, and so forth.

It’s an example of elements coming together for a movement, like this article says:

A movement occurs when, one, a large number of people have a need that, two, lines up with the necessary ingredients to make it happen, and those two things are sparked by, three, a catalyst.

The need to survive has always been here. The ingredients have been getting added to the mix since the dawn of the Scientific Revolution. The element of the love for life is in the air, thick with explosive properties, fueled by indefinite-life-extension research and outreach from around the world and across time. People are busy working on rallies, conferences, events, interviews, getting the message out, and all the rest. The tools and the ability to make this happen are ripe, and growing more and better yields of produce by the month. Every time you put a match to it, it erupts in indefinite-life-extension activism. Be that spark today and get in on this movement.

We have more projects like this ahead, and there are plenty of others to choose from in the communities, pages, groups, organizations, sites, and other venues, around the world, growing here toward that tipping point where we can have the opportunity to spill across the ticker tapes of screens and the minds of the young and old alike, lighting hearts and minds on fire with desire to chip in together to make this happen. This is an incredible opportunity, this time here, fertile with tools and insights, unleashed capabilities beyond our wildest dreams. People are already capable of tons of incredible things that you don’t even know about yet.

Columbus went on a fantastic voyage. When you think of those times, and how fulfilling and enthralling it must have been for them to be able to be part of that, realize that indefinite life extension, all this Transhumanism, is an even greater frontier, and you are in an even more incredible and glorious position than people like Columbus and his crew. It’s a position here where anybody, where you, can help sail out into these incredible frontiers that are opened up through the ever-expanding fields of science and technology.

Eric Schulke was a director at LongeCity during 2009-2013. He has also been an activist with the Movement for Indefinite Life Extension and other causes for over 13 years.

Death is Wrong - by Gennady Stolyarov II, Illustrated by Wendy Stolyarov

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