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Fundraiser by Lifespan.io & CellAge: Targeting Senescent Cells With Synthetic Biology

Fundraiser by Lifespan.io & CellAge: Targeting Senescent Cells With Synthetic Biology

The New Renaissance HatCellAge
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Editor’s Note: The Rational Argumentator and the U.S. Transhumanist Party support Lifespan.io and CellAge in their work towards groundbreaking scientific life-extension research. Finding a way to repair age-related damage to senescent cells would be a fundamental breakthrough for transhumanism, and we offer our best wishes and support for those striving towards these new technologies.

               ~ Gennady Stolyarov II, Editor-in-Chief, The Rational Argumentator, December 11, 2016

From Lifespan.io and CellAge:

Our society has never aged more rapidly – one of the most visible symptoms of the changing demographics is the exponential increase in the incidence of age-related diseases, including cancer, cardiovascular diseases and osteoarthritis. Not only does aging have a negative effect on the quality of life among the elderly but it also causes a significant financial strain on both private and public sectors. As the proportion of older people is increasing so is health care spending. According to a WHO analysis, the annual number of new cancer cases is projected to rise to 17 million by 2020, and reach 27 million by 2030. Similar trends are clearly visible in other age-related diseases such as cardiovascular disease. Few effective treatments addressing these challenges are currently available and most of them focus on a single disease rather than adopting a more holistic approach to aging.

Recently a new approach which has the potential of significantly alleviating these problems has been validated by a number of in vivo and in vitro studies. It has been demonstrated that senescent cells (cells which have ceased to replicate due to stress or replicative capacity exhaustion) are linked to many age-related diseases. Furthermore, removing senescent cells from mice has been recently shown to drastically increase mouse healthspan (a period of life free of serious diseases).

Here at CellAge we are working hard to help translate these findings into humans!

CellAge, together with a leading synthetic biology partner, Synpromics, are poised to develop a technology allowing for the identification and removal of harmful senescent cells. Our breakthrough technology will benefit both the scientific community and the general public.

In short, CellAge is going to develop synthetic promoters which are specific to senescent cells, as promoters that are currently being used to track senescent cells are simply not good enough to be used in therapies. The most prominently used p16 gene promoter has a number of limitations, for example. First, it is involved in cell cycle regulation, which poses a danger in targeting cells which are not diving but not senescent either, such as quiescent stem cells. Second, organism-wide administration of gene therapy might at present be too dangerous. This means senescent cells only in specific organs might need to be targeted and p16 promoter does not provide this level of specificity. Third, the p16 promoter is not active in all senescent cells. Thus, after therapies utilizing this promoter, a proportion of senescent cells would still remain. Moreover, the p16 promoter is relatively large (2.1kb), making it difficult to incorporate in present gene therapy vehicles. Lastly, to achieve the intended therapeutic effect the strength of p16 promoter to drive therapeutic effect might not be high enough.

CellAge will be constructing a synthetic promoter which has a potential to overcome all of the mentioned limitations. A number of gene therapy companies, including uniQure, AGTC and Avalanche Biotech have successfully targeted other types of cells using this technology. With your help, we will be able to use same technology to develop tools and therapies for accurate senescent cell targeting.

Crowdfunding Longevity Science: An Interview with Keith Comito of Lifespan.io – Article by Reason

Crowdfunding Longevity Science: An Interview with Keith Comito of Lifespan.io – Article by Reason

The New Renaissance HatReason
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Keith Comito leads the volunteers of the non-profit Life Extension Advocacy Foundation (LEAF) and the crowdfunding initiative Lifespan.io, a site I’m sure you’ve seen at least in passing by now. The LEAF crew have put in a lot of effort to help make fundraisers for rejuvenation research projects a success both last year and this year. Two such crowdfunding campaigns are running right now, firstly senolytic drug research at the Major Mouse Testing Program with just a few days left to go, and in its stretch goals, and secondly the recently launched drug discovery for ALT cancers at the SENS Research Foundation. Both tie in to the SENS portfolio of research programs aimed at effective treatment of aging and all age-related conditions. These are large projects when taken as a whole, but the way forward in this as in all things is to pick out smaller, achievable goals, and set out to get them done. Then repeat as necessary.

I recently had the chance to ask Keith Comito a few questions about Lifespan.io, the state of funding for the interesting end of longevity science, and what he envisages for the years ahead. This is an interesting, revolutionary time for the life sciences, in which progress in biotechnology has made early stage research very cheap. A great deal can be accomplished at the cutting edge of medical science given access to an established lab, administrators who can break out small initiatives from the larger goals, smart young researchers, and a few tens of thousands of dollars. It is an age in which we can all help to advance the research we care about, by collaborating and donating, and it has never been easier to just reach out and talk to the scientists involved. If you haven’t taken a look at Lifespan.io and donated to one of the projects there, then you really should. This is a way to move the needle on aging research, and advance that much closer to effective treatments for the causes of aging.

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What is the Lifespan.io story in brief? What was the spur that made you come together and decide to do your part in the fight against aging?

Lifespan.io began to take shape at the tail end of 2012, as a result of a loose discussion group based in New York which consisted of citizen scientists such as myself and Dr. Oliver Medvedik, supporters of SENS, as well as a few healthcare practitioners. We began having monthly meetings to discuss what could be done to accelerate longevity research (usually in oddball locations like salad bars or subterranean Japanese restaurants befitting our motley crew) and eventually hit upon the idea of crowdfunding. What drew us to this idea was that it was something tangible: a concrete way to move the needle on important research not only through funds, but through raised awareness. It is fine to talk and rabble-rouse about longevity, but we felt such efforts would be much more effective if they were paired with a clear and consistent call to action – a path to walk the walk, so to speak. As this idea coalesced we formed the nonprofit LEAF to support this initiative, and the rest is history. Not every one from the initial discussions in 2012 remained throughout the intervening years, but we are thankful to all who gave us ideas in those early days of the movement.

I’d like to hear your take on why we have to advocate and raise funds at all – why the whole world isn’t rising up in support of treatments for the causes of aging.

The reasons why people and society at large have not prioritized anti-aging research thus far are myriad: fear of radical change, a history of failed attempts making it seem like a fools errand, long timescales making it a difficult issue for election-focused politicians to support, etc. The reason I find most personally interesting relates to cognitive bias – specifically the fact that our built-in mental hardware is ill-equipped to handle questions like “do you want to live 100 more years?” If instead you ask the questions “Do you want to be alive tomorrow?” and “Given that your health and that of your loved ones remains the same, do you suspect your answer to the first question will change tomorrow?”, the answers tend to be more positive.

This leads me to conclude that the state of affairs is not necessarily as depressing for our cause as it might appear, and that reframing the issue of healthy life extension in a way that will inspire and unite the broader populace is possible. Aubrey de Grey has spoken about “Longevity Escape Velocity” in relation to the bootstrapping of biomedical research, but I think the same idea applies to the public perception of life extension as well. The sooner we can galvanize the public to support therapies that yield positive results the easier it will become to invite others to join in this great work. It is all about jump starting the positive feedback loop, and that is why we believe rallying the crowd behind critical research and trumpeting these successes publicly is so vitally important.

What the future plans for Lifespan.io and the Life Extension Advocacy Foundation?

In addition to scaling up our ability to run successful campaigns on Lifespan.io, we look forward to improving our infrastructure at LEAF by bringing on some staff members to join the team. LEAF has largely been a volunteer effort thus far, and having the support of a staff will allow us to take on more campaigns as well as further improve the workflow to create and promote them. This will also free me up personally to more actively pursue potential grand slams for the movement, such as collaborations with prominent YouTube science channels to engage the public and policy related goals like the inclusion of a more useful classification of aging in the ICD-11.

Do you have any favored areas in research at the moment? Is there any particular field for which you’d like to see researchers approaching you for collaboration?

Senolytics is certainly an exciting area of research right now (congratulations Major Mouse Testing Program!), and a combination of successful senolytics with stem cell therapies could be a potential game changer. That being said I’d also like to see projects which address the truly core mechanics of aging, such as how damage is aggregated during stem cell division, and the potential differences in this process between somatic and germ cells. How can the germ line renew itself for essentially infinity? The real mystery here is not that we grow old, but how we are born young.

A related question: where do you see aging and longevity research going over the next few years?

In the near future we will likely continue to see the pursuit of compounds which restore bodily systems failing with age to a more youthful state. This will include validating in higher organisms molecules that have shown this sort of promise: rapamycin, metformin, IL-33 for Alzheimer’s, etc. This approach may sound incremental, but it actually signals a great paradigm shift from the old system of mostly ineffective “preventative measures” such as antioxidants. Things like nicotinamide mononucleotide (NMN), IL-33 – if successful these types of therapies can be applied when you are old, and help restore your bodily systems to youthful levels. That would be a pretty big deal.

Funding is ever the battle in the sciences, and especially for aging. Obviously you have strong opinions on this topic. How can we change this situation for the better?

I believe the key to greater funding, both from public and private sources, is to build up an authentic and powerful grassroots movement in support of healthy life extension. Not only can such a movement raise funds directly, but it also communicates to businesses and governments that this is an issue worth supporting. An instructive example to look at here is the work of Mary Lasker and Sydney Farber to bring about the “War on Cancer”. Through galvanizing the public with efforts such as the “Jimmy Fund”, they effected social and political change on the issue, and helped turn cancer from a pariah disease into a national priority. If we all work together to build an inclusive and action-orientated movement, we can do the same.

Reason is the founder of The Longevity Meme (now Fight Aging!). He saw the need for The Longevity Meme in late 2000, after spending a number of years searching for the most useful contribution he could make to the future of healthy life extension. When not advancing the Longevity Meme or Fight Aging!, Reason works as a technologist in a variety of industries.
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This work is reproduced here in accord with a Creative Commons Attribution license. It was originally published on FightAging.org.

 

G. Stolyarov II Interviews Demian Zivkovic Regarding the D.N.A. – Gene Therapies Congress

G. Stolyarov II Interviews Demian Zivkovic Regarding the D.N.A. – Gene Therapies Congress

The New Renaissance Hat
G. Stolyarov II and Demian Zivkovic
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Mr. Stolyarov invited Demian Zivkovic, President of the Institute of Exponential Sciences (IES), to discuss the forthcoming Designing New Advances (D.N.A.) Gene Therapies Congress in Utrecht, The Netherlands.

The interview took place on Sunday, June 19, 2016, at 11 a.m. US Pacific Time. Watch the recording here.

The D.N.A. Congress is scheduled to occur on July 9, 2016, and will feature speakers such as Oliver Medvedik, Aubrey de Grey, Elizabeth Parrish, Keith Comito, and Tatjana Kochetkova. This event receives the strong endorsement of both The Rational Argumentator and the Nevada Transhumanist Party.

Read the announcement of the D. N. A. Congress here.

Contribute to the fundraiser for the D. N. A. Congress on Indiegogo  and Generosity.

DNA_Interview_CoverDemian Zivkovic is the president of the Institute of Exponential Sciences  (Facebook  / Meetup) – an international transhumanist think tank / education institute comprised of a group of transhumanism-oriented scientists, professionals, students, journalists, and entrepreneurs interested in the interdisciplinary approach to advancing exponential technologies and promoting techno-positive thought. He is also an entrepreneur and student of artificial intelligence and innovation sciences and management at the University of Utrecht.

Demian and the IES have been involved in several endeavors, such as organizing lectures on exponential sciences, interviewing experts such as Aubrey de Grey, joining several of Mr. Stolyarov’s futurism panels, and spreading Death is Wrong – Mr. Stolyarov’s illustrated children’s book on indefinite life extension – in The Netherlands.

Demian Zivkovic is a strong proponent of healthy life extension and cognitive augmentation. His interests include hyperreality, morphological freedom advocacy, postgenderism, and hypermodernism. He is currently working on his ambition of raising enough capital to make a real difference in life extension and transhumanist thought.

D.N.A. Congress Announcement by the Institute of Exponential Sciences

D.N.A. Congress Announcement by the Institute of Exponential Sciences

The New Renaissance HatInstitute of Exponential Sciences
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Editor’s Note: The forthcoming D.N.A. Congress in Utrecht, The Netherlands, hosted by the Institute of Exponential Sciences, devoted to discussions of gene therapies, receives the strong endorsement of both The Rational Argumentator and the Nevada Transhumanist Party. The D.N.A. Congress offers a promising venue to discuss the potential for gene therapies to cure diseases, lengthen lifespans, and improve quality of life for millions of people in the coming years and decades.

~ Gennady Stolyarov II, Editor-in-Chief, The Rational Argumentator, June 5, 2016

D.N.A CONGRESS PRESS RELEASE:

The Institute of Exponential Sciences (IES) has a large announcement to make. We are organising D.N.A – The largest European congress on human gene therapies, featuring speakers such as Aubrey de Grey, Liz Parrish, Oliver Medvedik and others.

Our event has been endorsed by LEAF, Heales VZW, BioViva, SENS Research Foundation, Singularity Network, People Unlimited, The Rational Argumentator, and many others. The event will be covered by national media and will be broadcasted online.

To make this vision a reality, we need your support. Share this message and donate today. Thank you!

IES needs your support to help make this vision a reality. Click here to donate to our crowdfunding campaign.

D.N.A – Designing New Advances: The second large Institute of Exponential Sciences event is coming to Utrecht

 

DNADemian Zivkovic

Utrecht – After a successful event last year in May, the grand congress is ready for a second edition. With a new name, we hope to make exponential sciences more approachable to the general public and bring people in the field closer together. The Institute of Exponential Sciences congress 2016 will be held at RASA podium on the 9th of July. The main theme of the event is gene therapies and cutting-edge applications of such therapies, such as health extension and interventions against human aging. To guarantee a great event, we have invited some of the biggest names in the field. Our guest speakers will be as follows:

Opening the event will be Oliver Medvedik, Ph.D, director of scientific programs at Genspace. Dr. Medvedik has earned his Ph.D at Harvard Medical school in the biomedical and biological sciences program. Since graduating from Harvard, he has worked as a biotechnology consultant, taught molecular biology to numerous undergraduates at Harvard, and mentored two of Harvard’s teams for the international genetically engineered machines competition (IGEM) held annually at M.I.T.

Our second speaker is Aubrey David Nicholas Jasper de Grey, Ph.D, an English author, Chief Science Officer of the SENS Research Foundation, and editor-in-chief of the academic journal Rejuvenation Research. Aubrey de Grey is well known for his focus on regenerative medicine and views on human aging. He will take the stage talking about the applications of current and upcoming technologies and studies which hold the potential to greatly extend our healthy lifespan.

Our third speaker is Tatjana Kochetkova, Ph.D, who is a fellow of the Institute of Exponential Sciences and a bioethicist. Dr. Kochetkova will follow up discussing the ethical and philosophical side of the technology and will address questions of what exponential technologies in biotech mean for society.

Our fourth speaker is Elizabeth Parrish, a fellow of the Institute of Exponential Sciences and the Founder and CEO of BioViva Sciences Inc, a Delaware corporation based in Seattle, WA, with labs and participating clinics in South/Central America where the majority of practical work is carried out. BioViva has been noted for being the first corporation in the world to treat a patient with gene therapy to reverse aging. The woman who wants to genetically engineer you will cover the basics of BioViva’s approach and vision for the the future, as well as the potential that gene therapies hold for radically improving our health and lives in the future.

Our fifth speaker will be Keith Comito, who is the founder and president of the Life Extension Advocacy Foundation (LEAF), a 501(c)(3) non-profit organization and a partner of the Institute of Exponential Sciences. Through LEAF, he operates the crowdfunding platform Lifespan.io, which supports biomedical research aimed at extending healthy human lifespan. He also serves as policy coordinator for the Global Healthspan Policy Institute, which facilitates relationships between researchers and government to advance initiatives in support of healthy life extension.

About Institute of Exponential Sciences

The Institute of Exponential Sciences is an international innovation-oriented think tank, outreach organisation, and networking platform based in the Netherlands, in the city of Utrecht. Its main activities include organising lectures and conferences, providing quality consultancy on innovation and exponential technologies, and collaborating with student organisations and universities in educating the public on the importance of exponential technologies.

It was founded by members of its predecessor, the Arma’thwynn society, which was a student group of like-minded young academics in the Netherlands. After organising events and attracting a very diverse and professional team of entrepreneurs, academics, and journalists, the society decided to move past student politics and make the move towards professionalism.

The Institute of Exponential Sciences is the result of that decision. After organising successful events (the largest of which was their symposium in April, 2015), the Institute of Exponential Sciences formalised its mission and reached out towards a process of international collaboration with other entities which share a techno-positive vision. The institute strives towards excellence in providing the best information and resources related to the issues relevant in the rapidly advancing technological society we live in.

The IES approach is focused on providing interdisciplinary education in the fields of exponential technologies such as artificial intelligence, bio-informatics, gene therapies, 3D-printing, augmented reality, and neural interfacing. We also provide a networking platform which allows entrepreneurs, scientists, journalists, and students to get in touch with others with similar ideas so that they may create the technologies of tomorrow. The IES strives not only to improve the speed of development of these technologies, but also to show the public the amazing possibilities technology provides for society.

IES and the IES logo are either registered trademarks or trademarks of IES Foundation in the Netherlands and/or other countries. All other products and/or services referenced are trademarks of their respective entities.

Major Mouse Testing Program Crowdfunding Campaign Announcement by International Longevity Alliance

Major Mouse Testing Program Crowdfunding Campaign Announcement by International Longevity Alliance

The New Renaissance HatInternational Longevity Alliance

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Editor’s Note: The Rational Argumentator strongly supports the Major Mouse Testing Project crowdfunding campaign, and I have personally pledged $100 to this effort. Furthermore, I am honored that copies of my illustrated children’s book Death is Wrong are being made available as rewards for certain tiers of contributors to this research fundraiser.

~ Gennady Stolyarov II, Editor-in-Chief, The Rational Argumentator, May 11, 2016

The International Longevity Alliance is conducting a crowdfunding campaign to support the investigation of senolytic drugs’ potential to extend life. The team is going to study the combination of three senolytic drugs – Dasatinib, Venetoclax, and Quercetin – in mice, to see if the removal of senescent cells can ensure extended maximum lifespan. With highly devoted scientists and volunteers working for MMTP, the project needs only $60,000 to begin this experiment, as the researchers would need only to buy the mice and pay for their housing, the substances to test, and the battery of tests to analyze health changes.

Will you help to fund this research? Then please go to Lifespan.io, and choose the donation that suits you best and receive the deepest gratitude of the team and a nice useful souvenir to remember your input into the investigation of longevity therapies!

MMTP_Project1_StairFind out more about the International Longevity Alliance here.

Lifespan Challenge: Support the MitoSENS Mitochondrial Repair Project Research Fundraiser – Video by G. Stolyarov II

Lifespan Challenge: Support the MitoSENS Mitochondrial Repair Project Research Fundraiser – Video by G. Stolyarov II

The New Renaissance HatG. Stolyarov II
October 21, 2015
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Mr. Stolyarov, author of “Death is Wrong” and Chief Executive of the Nevada Transhumanist Party (NTP), challenges all members of the NTP and the general public to donate to life-extension research – particularly, the ongoing MitoSENS Mitochondrial Repair Project for which crowdfunding is currently being conducted on Lifespan.io.

LifespanChallengeSign-513x396

International Longevity Day – October 1, 2015 – Press Release by Ilia Stambler

International Longevity Day – October 1, 2015 – Press Release by Ilia Stambler

The New Renaissance HatIlia Stambler
August 30, 2015

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International-Longevvity-Day Dear friends,

There has been emerging a tradition by longevity researchers and activists around the world to organize events dedicated to promotion of longevity research on or around October 1 – the UN International Day of Older Persons.

This day is sometimes referred to in some parts of the longevity activists community as the “International Longevity Day”. As this is the official UN Day of Older Persons, this provides the longevity research activists a perfect opportunity, perhaps even a perfect “excuse”, to emphasize the importance of aging and longevity research for the development of effective health care for the elderly, in the wide public as well as among decision makers.

The critical importance and the critical need to promote biological research of aging derives from the realization that tackling the degenerative processes and negative biological effects of human aging, at once and in an interrelated manner, can provide the best foundations to find holistic and effective ways for intervention and prevention against age-related ill health. Such an approach has been supported by scientific proofs of concept, involving the evidential increase in healthy lifespan in animal models and the emerging technological capabilities to intervene into fundamental aging processes. The focus on intervention into degenerative aging processes can provide solutions to a number of non-communicable, age-related diseases (such as cancer, heart disease, type 2 diabetes and neurodegenerative diseases), insofar as such diseases are strongly determined by degenerative aging processes (such as chronic inflammation, cross-linkage of macromolecules, somatic mutations, loss of stem cell populations, and others). This approach is likely to decrease susceptibility of the elderly also to communicable, infectious diseases due to improvements in immunity. The innovative, applied results of such research and development will lead to sustainable, economically viable solutions for a large array of age-related medical and social challenges, that may be globally applicable. Furthermore, such research and development should be supported on ethical grounds, to provide equal health care chances for the elderly as for the young.

Therefore it is the societal duty, especially of the professionals in biology, medicine, health care, economy and socio-political organizations, to strongly recommend greater investments, incentives and institutional support for the research and development dealing with the understanding of mechanisms associated with the human biological aging process and translating these insights into safe, affordable and universally available applied technologies and treatments.

October 1 – the International Day of Older Persons — provides the researchers and advocates an opportunity to raise these points and make these demands.

http://www.longevityforall.org/the-critical-need-to-promote-research-of-aging-around-the-world/

In 2013, events during or around that day – ranging from small meetings of friends to seminars and rather large conferences, alongside special publications, distributions of outreach materials (petitions and flyers) and media appearances – were held in over 30 countries, and in 2014 in over 20 countries. (Sometimes the events’ dates vary several days around October 1, or even through the entire month of October, designated as the “International Month of Older Persons” or the “International Longevity Month”, and sometimes the events are organized independently and without prior knowledge of other events, but they are all nonetheless unified by the common action and purpose.)

http://www.longevityforall.org/october-1-international-day-of-older-persons-longevity-day-2013-2014/

Let us maintain and strengthen this tradition! Let us plan and organize a mutually reinforcing network of events worldwide. If you plan to organize an event for that day – either live meetings or on-line publications and promotions – please let know. Together we can create an activism wave of strong impact. 

Following the collection of an impressive number of longevity promoting events worldwide in honor of that day, a general public appeal will be issued, both widely disseminated and addressed to relevant officials, both governmental and supra-governmental. Yet, the strength of the appeal will depend on the strength of all the individual events and actions.

Among the materials for discussion, distribution and promotion, one may use the position paper on the “Critical need to promote research of aging and aging-related diseases to improve health and longevity of the elderly population”, briefly describing the rationales, technologies and policies needed to promote this research. The position paper is available in 9 languages and can serve as a “universal advocacy paper” both for the grass roots discussions and promotions and for the outreach to officials: http://www.longevityforall.org/the-critical-need-to-promote-research-of-aging-around-the-world/. Also one may use in the preparation a presentation briefly listing some topics in longevity science promotion, such as the feasibility and desirability of achieving healthy longevity and public actions that can be taken to achieve it – http://www.longevityhistory.com/articles/ab7.php – or any other materials of your choice.

So far, events for that day – including meetings, publications and promotions – are already planned to be held around the world, in over 30 countries on 5 continents, including:

In the US, a conference will be held at the headquarters of the International Society on Aging and Disease (ISOAD), at the University of North Texas Health Science Center, in Fort Worth, Texas. This action will be endorsed and promoted by the US Healthspan Campaign (http://www.healthspancampaign.org/).

The Longevity Day action will also be promoted by the US Transhumanist Party, during their campaign tour that coincides with October 1.

Also in the US, online promotions will be held by the MILE campaign and by the Christian Transhumanist Association.

MILE-Panel-Cover

A special promotion will be done by LEAF – Life Extension Advocacy Foundation – via its crowdfunding platform for longevity research (http://www.lifespan.io/).

A fundraising action will be launched on that day for SENS Research Foundation by Fight Aging (https://www.fightaging.org/fund-research/).

In Israel, a seminar will be held in Bar Ilan University, by the Israeli Longevity Alliance. Toward that day, Israeli activists will also freely distribute an e-book on the history of longevity research (http://www.longevityhistory.com/).

In Moscow, Russia, a conference will be organized by the Russian Longevity Alliance. Another large conference will take place in Moscow, on the “Quality of Life of Older Persons”, supported by the Gerontological Society of the Russian Academy of Sciences, focusing on geroprotective substances and therapies.

In Gomel, Byelorussia, at the end of September, a conference will take place on the general subject of Radiobiolgy, at the Institute of Radiobiology of the National Academy of Sciences of Byelorussia, with a leading section on the biology of aging and longevity (“gerontological aspects of man-made factors”).

Another  small conference will take place in New Delhi, India, organized by the Solutions For the Future, with the help of India Future Society, and ISOAD India.

A series of events is planned in Pakistan, by the Pakistan National Academy of Young Scientists and the Universities of Lahore and of Malakand. The newly formed Pakistan Aging Research Society (PARS) organizes an entire month long campaign, “Go for Life” – from September 1 until October 1 – to encourage physical activity of older persons.

In Rome, Italy, a conference will be organized by the Italian Transhumanist Association and the Italian Longevity Alliance.

Additional meetings and promotions are planned by the European Healthy Life Extension Society (HEALES) in Brussels, Belgium, including a Competition for the Best Short Film on Life Extension.

A conference on longevity/life-extension science will be held by the Waag Society – Do It Together Bio in Amsterdam, Netherlands.

In Germany, meetings will be held by two new officially registered political parties that emphasize the development of biomedical research in their programs: in Berlin, by the German Health Research Party and in Stuttgart by the German Transhumanist Party.

An online promotion (videoconference) in Spanish will be organized by the Venezuela Longevity Alliance (together with activists from accross Latin America). A similar videoconference (to be recorded) in Portuguese will be organized for Brazil by the Brazil Longevity Alliance.

A pro-longevity documentary promotion will be done in Helsinki by Longevity Finland – Pitkäikäinen Suomi.

A meeting will be held in Stockholm, Sweden, by Aldrandefonden/Svenska Livsförlängningssällskapet SLFS – Swedish Life Extension Society.

In the UK, the London Futurist community will celebrate longevity research as a part of a discussion of emerging technologies in London.

In Larnaca, Cyprus, the ELPIS Foundation, together with the local gerontological community, will hold a seminar “Health in Older Life” and a local TV show in honor of that day.

In Perth, Australia, a meeting will be held by the “Healthy Longevity Philosophy” society. Another promotion will be done by Science, Technology and the Future society in Melbourne, Australia.

In Kiev, Ukraine, a seminar will be held on behalf of the Kiev Institute of Gerontology of the Ukrainian Academy of Medical Sciences.

In Beijing, China, a meeting will be organized by the Technium community.

In Uganda, the Kasese Freethinkers Sports Academy will educate about the connection between physical activity and longevity.

A mini-seminar will be held in Lekki, Lagos, Nigeria, by Longevity Nigeria group.

In Romania, a conference will be held at Äna Aslan National Institute of Gerontology and Geriatrics, in Bucharest, toward the end of October, with earlier promotions.

In Vietnam, Hanoi, the Vietnam Public Health Association will hold a conference on the Mental Health of the Elderly, emphasizing biomedical research on neurodegenerative diseases.

In Singapore, a seminar on biology of aging will be organized at the National University of Singapore. This will precede a large Biology of Aging Conference organized by the Singapore Immunology Network (A*Star) – not “officially” a part of the “Longevity Day” events, but perhaps of the “Longevity Month.”

At about the same time, the 10th Asia / Oceania Congress of Gerontology and Geriatrics 2015 for “Healthy Aging Beyond Frontiers” will take place in Chiangmai, Thailand, including sections on biology of aging.

In Paris, France, a seminar will be organized at the Biopark Cancer Campus, University Paris Sud.

In South Korea, the Korean Branch of Solutions for the Future will organize a meetup in Seoul.

In Switzerland, Zurich, the Swiss Longevity Alliance will have a presentation on longevity research. This will shortly follow a large international symposium on geroprotectors in Basel.

In Poland, the Warsaw University Students Association will support the organization of a discussion on life extension science.

In Canada, at Huntington University, an event will be held by the Canadian Institute for Studies in Aging (CISA). In Alberta University, Canada, a special discussion on Technology and the Future of Medicine will be dedicated to that day.

In Iran, a study group will be conducted in Tehran on behalf of the Iran Longevity Alliance: http://www.iranlongevity.com/.

Yet another study group will be held in Cairo, Egypt, by the Egypt Longevity Alliance: http://www.egyptplus.org/.

And yet another free discussion of longevity science will take place in Tirana, Albania – the first longevity research activism event in the country.

In Bulgaria, events toward the International Longevity Day will start earlier in September with a conference in Ravda, organized by the University for National and World Economy, Department of Management and BASAGA – Bulgarian Academic Simulation and Gaming Association, including a section on Futurism, Transhumanism and Longevity, and continuing up to the date itself with more live and online discussions and publications and a special appeal in honor of that day.

In Tokyo, Japan, Exponential Technologies Institute will hold a meetup on longevity science in the framework of Tokyo-Singularity-Meetup.

A meeting will be held in the National Library in Tbilisi, Georgia, by activists of the Georgian Longevity Alliance, including presentations on the development of longevity science in Georgia and the world, and debates.

More events and expressions of support are expected to be initiated in the very near time in different countries.

Please add your support and more events and publications for this initiative! If you would like to get involved, please let know!

You are also welcome to promote this initiative on social media:

https://www.facebook.com/events/1017229998296364/

https://www.facebook.com/LongevityDay

Preparations for the next year’s International Longevity Day – October 1 – already started as well. The next global conference of the International Society on Aging and Disease (ISOAD) will take place in Stanford on October 1-2, 2016. The topics will range from interventions for longevity through stem cell research, genetics and systems biology of aging, to public support for aging research. The submission of abstracts and proposals is already started and welcome. And a conference is being planned in Brussels, for September 29-October 1, 2016, by the European Healthy Life Extension Society – Heales.

Hopefully, thanks to these and many other events, in this year and in the years to come, the importance of biological aging and longevity research will gradually become a strong theme of the international healthcare agenda, for the elderly and for the entire population.

Ilia Stambler, PhD.

Outreach coordinator. International Society on Aging and Disease (ISOAD)

http://isoad.org/

ilia.stambler@gmail.com

Thank you!

Ilia Stambler, Ph.D. is an IEET Affiliate Scholar, researcher at Bar-Ilan University, Israel, and activist at the International Longevity Alliance. He is author of A History of Life-Extensionism in the Twentieth Century.
 
He studied biomedical engineering at the Moscow Polytechnical Institute, biology at the Technion, Israel Institute of Technology, and earned his MA in English literature from Bar-Ilan University. He earned his Ph.D. at the Department of Science, Technology, and Society, at Bar-Ilan University. His thesis subject, and his main interest, is the History of Life-Extensionism in the Twentieth Century.
 
In addition, Ilia authored Life extension — a conservative enterprise? Some fin-de-siècle and early twentieth-century precursors of transhumanism, Demonstration for Radical Life Extension in Tel Aviv, and Heroic Power in Thomas Carlyle and Leo Tolstoy, and coauthored Breast cancer detection by Michaelis–Menten constants via linear programming, and Comparative analysis of cell parameter groups for breast cancer detection. Read the full list of his publications!
 
He speaks Hebrew, English, Russian, German, and Yiddish. He is active in the Israeli chapter of Humanity Plus, the Israeli Society for the Biology of Aging, and the International Longevity Alliance.
 
Watch Demonstration for Radical Life Extension in Tel Aviv 5: Ilia Stambler. Read 10 Answers by Ilia Stambler. Visit his Facebook page. Read his Google+ profile and his LinkedIn profile. Read his blog Singularity | Life Extension | Transhumanism (Hebrew).