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Life-Extension Activism Opportunities for All – Article by G. Stolyarov II

Life-Extension Activism Opportunities for All – Article by G. Stolyarov II

The New Renaissance Hat
G. Stolyarov II
June 5, 2014
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You do not need to be a biologist or medical doctor to help hasten the arrival of indefinite life extension. An important array of activist endeavors, which are laying the groundwork for the eventual achievement of unlimited lifespans, can be implemented by anybody. They range from giving out books to playing games to simply running one’s computer – all the while making important contributions to scientific progress and the receptiveness of the general culture to the feasibility and desirability of indefinite longevity.

If you want to glimpse the possibilities in 90 seconds, watch my recent video, “What Anyone Can Do to Advance Indefinite Life Extension”.

In this article, I offer a more detailed overview of some immediately available activism options that anyone can pursue. The time commitment involved in each ranges from minimal to modest, but virtually any of them can fit into the schedule of anyone who recognizes the value of this amazing life we have and the importance of prolonging it as far as possible.

Movement for Indefinite Life Extension (MILE)

MILE_Logo
The Movement for Indefinite Life Extension (MILE) is not a formal organization, but rather a coalition of activists working toward the common goal of achieving indefinite lifespans for people alive today. The MILE coordinates projects and shares articles, images, and news stories via its Facebook group – also accessible using the URL http://themile.info. One of the MILE’s major purposes is to raise awareness of the feasibility and desirability of indefinite life extension and to create a critical mass of support for this most vital of goals. The number of “likes” on the MILE Facebook page is a concise indicator of the movement’s reach, and the eventual goal of the MILE is to achieve 8 million likes by July 17, 2017. Following an incremental approach, the MILE seeks to raise its support by an order of magnitude each year. The goal of 800 supporters was readily exceeded prior to July 17, 2013, and the MILE has launched a concerted effort to reach its Year 2 goal of 8,000 supporters by July 17, 2014. Eric Schulke, who spearheads and coordinates the efforts of the MILE, has launched the MILE Year 2 Goal Fundraiser to fund hundreds of dollars of Facebook advertisements that have already shown success in spreading the message of indefinite life extension to new demographics.

I am proud to have contributed resources to run several ads for MILE that incorporate the core message and the cover image of my children’s book Death is Wrong. These MILE/Death is Wrong ads were designed by my wife and illustrator Wendy Stolyarov and are accompanied by the following text:

Death is WRONG.
Together we can fight it.
Join the Movement for Indefinite Life Extension.

Reaper_MILE_Ad_FBDIW_MILE_AdTo help the MILE reach its Year 2 goal, you can start by clicking the “Like” button on the MILE Facebook page. Beyond that, if you would like to contribute to the advertising campaign and even develop your own custom advertisement that conveys the message of indefinite life extension, this would go a long way toward building the critical mass needed to catalyze public support for life-extension research.

Death is Wrong Book Distribution to Children

DIW_HannaAfter the successful conclusion on April 23, 2014, of my Indiegogo fundraiser to spread over 1,000 copies of the illustrated children’s book Death is Wrong to kids, free of cost to them, I have worked assiduously to coordinate a worldwide distribution effort. Already, 644 out of the 1,029 total available books have been sent to longevity activists throughout the world. Countries where the books have been shipped thus far include the United States, Canada, Mexico, the United Kingdom, the Netherlands, Poland, India, Indonesia, and Singapore. Tens of dedicated longevity supporters have already come forward to request absolutely free shipments of books, but we need more activists to help us distribute the remaining 385 books in their local areas.

Recipients have wide discretion to use their creativity in how to offer the Death is Wrong books to children, as long as the books are made available free of cost and are not resold. Books may be given away to kids directly, lent to multiple kids, given to schools and libraries that will accept them, or used at public readings – among possible other options.

The early successes of the book-distribution effort are among the most heartening and encouraging developments I have observed. Here are some photographs that longevity activists have sent in of their book shipments.

DIW_Amechazurra_ShipmentDIW_Books_Received_CvdB_3
DIW_Books_Received

Here is a charming interview by Aleksander Kelley of his sister Hanna, who is spreading Death is Wrong to the kids she knows.

Help make future scenes like this happen. Requesting a shipment of Death is Wrong books is simple. Send me an e-mail to gennadystolyarovii@gmail.com with (i) your name, (ii) your mailing address, (iii) your statement of support for indefinite life extension, (iv) the number of copies of Death is Wrong requested, and (v) your plan for spreading the books to children, free of cost to them.

Once the shipments arrive, any additional images and videos of the books and events at which they are shared would be most welcome. They can help spread the message of indefinite life extension even further and show the world that the momentum for this cause continues to grow.

Distributed Computing for Medical Science

Would you like to help cure cancer, Alzheimer’s disease, Huntington’s disease, and other deadly ailments, just by running your computer? Most people’s computers spend much time absolutely idle; how about putting that idle time to good use, at minimal additional cost? Distributed computing initiatives such as Folding@home, Rosetta@home, and World Community Grid are absolutely free to join. You just need to download a program that runs the calculations involved in protein-folding simulations and other research efforts while you are not using your computer. Already, these distributed computing initiatives have led to several major medical research breakthroughs, such as this one by Chiba Cancer Center in Japan, which has identified seven drug candidates in the fight against childhood cancer. You can read more about the applications of protein-folding simulations to disease research in this brief post by David Baker of the University of Washington.

While no single medical breakthrough will achieve indefinite lifespans yet, every victory against death and diseases will help us approach that goal. The more of us survive the common killers of our time, the more of us stand a chance of personally witnessing the arrival of longevity escape velocity.

As an additional way to raise the profile of the ideas of indefinite life extension, it is recommended to join a distributed-computing team that explicitly embraces the struggle against senescence and death. On Folding@home, The Longevity Meme team has been folding for years and is ranked 156th out of 220,186 teams as of June 5, 2014. I am spearheading a collaborative effort between The Longevity Meme team, LongeCity, and my online magzine – The Rational Argumentator – to attract renewed participation in Folding@home and The Longevity Meme team among longevity advocates. To provide an additional incentive to join, I am offering a series of five Protein Folding for Life Extension Open Badges, designed by Wendy Stolyarov and available via Badg.us.

FaH-Square-L1 FaH-Square-L2 FaH-Square-L3 FaH-Square-L4 FaH-Square-L5These are badges that you can store and share via Mozilla Backpack to share your achievements with others. The following are the qualifying criteria for each badge:

Level 1: 5,000 points earned on Folding@home;

Level 2: 10,000 points earned on Folding@home;

Level 3: 50,000 points earned on Folding@home;

Level 4: 100,000 points earned on Folding@home;

Level 5: 500,000 points earned on Folding@home.

To request a badge, simply send an e-mail to gennadystolyarovii@gmail.com. Include your user name on Folding@home so that your points earned could be verified. You can earn a badge no matter what team you are on, if any, as everyone’s commitment of resources to the protein-folding effort helps the prospects of indefinite life extension. However, you are also encouraged to join The Longevity Meme team in order to help improve its ranking and raise public awareness of the effort life-extension activists are putting into the fight against disease.

On Rosetta@home, the LongeCity team explicitly embraces the ideas of indefinite life extension. On World Community Grid, the Endthedisease team supports life extension and has been involved in numerous disease-fighting computational efforts since 2007. Later this year, the Endthedisease team is anticipated to begin running contests with prizes for top contributors.

Games to Fight Disease

By flying a spaceship through an asteroid field in a computer game, you can help cancer researchers analyze data at a much faster rate than they could before. Play to Cure: Genes in Space is a mobile game released by Cancer Research UK, which anyone with a tablet or mobile phone can play for free. The stated aim of this game is to hasten the day when all cancers are cured – which is, incidentally, the key objective of one of the seven prongs of Dr. Aubrey de Grey’s SENS approach; Dr. de Grey has emphasized that cancer is by far the predominant way by which age-related nuclear mutations harm us.

You can read about the mechanics of and science behind Play to Cure here and watch this video introduction to the game.

Foldit is another free game that enthusiasts of life-extension research can play in order to add the human touch to protein-folding simulations. In 2011, Foldit players discovered the protein structure of a retroviral protease of the Mason-Pfizer monkey virus, an AIDS-like disease in monkeys.

See this list from the Citizen Science Center for more possibilities regarding games you could play and simultaneously participate in innovative citizen-science initiatives – including many devoted to the fight against disease. Games hold out the promise of enabling monumental contributions to scientific research by the general public. A game designed to be sufficiently engaging could attract thousands of non-scientists to do the work that research scientists could conceivably outsource in order to accelerate the rate at which certain kinds of data analysis are performed. The more quickly scientists can iterate through their experiments as a result, the sooner the cures to major diseases will arrive.

Conclusion

Of course, I would urge all life-extension supporters to donate even modest amounts of money to research and advocacy organizations such as the SENS Research Foundation and the Methuselah Foundation, as well as crowdfunded life-extension research projects that are being undertaken with increasing frequency. Yet, I hope that this overview has led readers to recognize that much can be done in addition to monetary donations. Integrate the active pursuit of indefinite longevity into your life, and you will continue to find easy but extremely important ways to become part of the solution to the most pressing problem of all time. Through our efforts, we will hopefully someday be able to celebrate humankind’s greatest victories in the fight against our mutual enemy: death.

What Anyone Can Do to Advance Indefinite Life Extension – Video by G. Stolyarov II

What Anyone Can Do to Advance Indefinite Life Extension – Video by G. Stolyarov II

Mr. Stolyarov provides a quick overview of ideas that anyone can implement to accelerate the pace of technological progress and bring about indefinite life extension for many who are alive today.

This is Mr. Stolyarov’s entry in the MILE Video Contest.

References
SENS Research Foundation
Methuselah Foundation
MILE – Movement for Indefinite Life Extension
Folding@home
The Longevity Meme Folding@home Team
Open Badges for Participating in Folding@home
Rosetta@home
World Community Grid
Foldit
Play to Cure

Computer Games, Distributed Computing, and Life Extension – Video by G. Stolyarov II

Computer Games, Distributed Computing, and Life Extension – Video by G. Stolyarov II

Imagine if it were possible to help cure disease and lengthen human lifespans simply by playing one’s computer games of choice. Here, Mr. Stolyarov describes a concept for doing just that, and he welcomes efforts from any of you to help bring it about.

Remember to LIKE, FAVORITE, and SHARE this video in order to spread rational discourse on this issue.

Support these video-creation efforts by donating here and here.

References
– “Computer Games, Distributed Computing, and Life Extension” – Article by G. Stolyarov II – The Rational Argumentator
Article and discussion on Transhumanity.net
Mr. Stolyarov’s Page of Distributed Computing Statistics
Rosetta@home
Folding@home
World Community Grid
Human Proteome Folding
Help Conquer Cancer
FoldIt
– “Public Solves Protein Structure” – Jef Akst – The Scientist – September 18, 2011
– “ALS Cause and Protein-Folding Prediction – Thoughts on Two Impressive Scientific Discoveries ” – Video by G. Stolyarov II – September 20, 2011

Computer Games, Distributed Computing, and Life Extension – Article by G. Stolyarov II

Computer Games, Distributed Computing, and Life Extension – Article by G. Stolyarov II

The New Renaissance Hat
G. Stolyarov II
February 26, 2013
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Imagine if it were possible to help cure disease and lengthen human lifespans simply by playing one’s computer games of choice. Here, I describe a concept for doing just that, and I welcome efforts from any readers to help bring it about.

To make a practical, concrete difference in accelerating the advent of radical human life extension, one of the most powerful contributions a layman (non-biologist, non-doctor, non-engineer) can make is to donate idle computer time to distributed computing projects focused on biomedical research. Immensely promising distributed computing endeavors include Rosetta@home, Folding@home, and World Community Grid’s Human Proteome Folding and Help Conquer Cancer projects.  I am a major participant in many of these projects. (I rank in the 98.6th percentile for all distributed computing users by total credit and in the 99.5th percentile by recent average credit.) My computer runs these projects almost nonstop, and I have even made several upgrades, partly to enhance my contribution.  Distributed computing enables scientific research to occur at rates and scales previously inconceivable. Researchers utilize thousands of computers worldwide to perform incredible numbers of complex calculations that they could not have processed in their labs alone.

Billions of computers now exist, and it seems so easy to just download a distributed computing client and let it run while the computer is idle. The computer owner does not need to be technically knowledgeable about the field of research in order to make a positive and direct contribution. Yet participation in distributed computing projects is still orders of magnitude below where it should be. For instance, as of February 23, 2013, Folding@home has 1,674,431 all-time donors of computer resources; the front page suggests that 167,833 computers are currently active in the project. Rosetta@home has 355,661 total donors, while World Community Grid has 401,270. The number of people worldwide who care about advancing medical research is surely far larger than this.

 Yet even an easy task like installing a distributed computing client may be beyond the comfort zone of many people with busy, often hectic, lives. If these people take time out of their day for activities not related to their primary occupations, they will do so because they find those activities entertaining, relaxing, or both. Computer games are an immensely popular example; they directly engage hundreds of millions of people worldwide for hundreds of billions of hours every year. If this level of contribution were made to distributed computing projects, we would see the pace of research accelerate tenfold or more.

There is already one game, FoldIt, that attempts to utilize human creativity to directly address one challenge related to life extension: the prediction of protein-folding configurations. FoldIt’s users have even had some success where computer algorithms have not. However, FoldIt’s gameplay is not for everyone, just like any particular genre of computer game will attract some enthusiastic users but will leave others indifferent.

To radically increase the use of distributed computing, I recommend a new approach: the design of computer games that automatically run distributed computing projects in the background when they are played. Players would not need to acquire the game with the purpose of contributing to research projects; their primary motivation should be to enjoy the game. However, one of the marketing points in the game’s favor could be that it would enable people to make a meaningful contribution to research while they enjoyed themselves. Such games would not need to be related to the subject of the research at all; they could be about absolutely anything, and there could be numerous games of this sort made to appeal to a wide variety of consumer demographics. Indeed, creators of existing games could work on ways to link them to distributed computing clients and use this to emphasize their companies’ philanthropic side.

Each game could include an option to activate the distributed computing client even if the game is not being played. In this way, players who come to enjoy their participation in distributed computing projects could extend that participation beyond their gaming sessions. On the other hand, a lot of players would acquire the game just to play it, while being only peripherally aware of the distributed computing aspect. However, their consent to the distributed computing would be a part of the usage agreement associated with the game. They would contribute to important biomedical research by default, just like all of us contribute to the carbon dioxide available to the Earth’s plants simply by exhaling.

I am not a programmer myself, but I strongly encourage any programmer and/or game developer reading this article to develop this proposed connection between any game and a distributed computing project. This concept should be in the public domain, and, to the extent this is possible under current law, I hereby release any original ideas or concepts in this article into the public domain in full. I seek no monetary profit or even credit from such undertakings (though I would be extremely happy to be informed of efforts to implement them). I will benefit considerably if the implementation of this idea radically accelerates life-extension research, and this benefit would certainly be enough for me.  It is in my best interest for numerous parallel, competing, or collaborative efforts to arise in this area, and for many people to try variations on this idea.

I also welcome input from those who can anticipate some of the technical details and challenges of developing games of this sort. For instance, I would be interested in insights regarding the potential ease or difficulty of integrating a distributed computing client with another program. At present, I anticipate that most of the challenges would be technical, rather than legal, since BOINC, one of the most popular clients, is free software released under a GNU Lesser General Public License. My strong recommendation is for any efforts in this area to have an open-source character, welcoming contributions from all parties in order to make the vast benefits of this project realizable. At least some of the games created as a result could be made freely downloadable, so as to entice more people into obtaining them with nothing to lose.

The idea is now out there. I urge you to help make it happen in any way you are able.