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RAAD Fest 2019 Announcement of U.S. Transhumanist Party 2019 Primary Election Results and Johannon Ben Zion Acceptance Speech

RAAD Fest 2019 Announcement of U.S. Transhumanist Party 2019 Primary Election Results and Johannon Ben Zion Acceptance Speech

Gennady Stolyarov II
Johannon Ben Zion


At RAAD Fest in Las Vegas on October 6, 2019, Gennady Stolyarov II, Chairman of the U.S. Transhumanist Party / Transhuman Party (USTP), announced the results of the 2019 USTP Electronic Primary for President of the United States, and introduced the winner of the Electronic Primary and the USTP-endorsed candidate for President of the United States in 2020, Johannon Ben Zion.

Watch the video recording of the announcement and Candidate Ben Zion’s acceptance speech here.

See the detailed results of the 2019 USTP Electronic Primary here.

Read about USTP’s endorsed candidate, Johannon Ben Zion, here.

Join the U.S. Transhumanist Party / Transhuman Party for free, no matter where you reside. Click here to apply in less than a minute.

The Rational Argumentator’s Seventeenth Anniversary Manifesto

The Rational Argumentator’s Seventeenth Anniversary Manifesto

The New Renaissance Hat
Gennady Stolyarov II
September 3, 2019
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The seventeenth year of The Rational Argumentator’s existence has been kind to us in terms of visitation. TRA attained 1,452,542 page views between September 1, 2018, and August 31, 2019, a count exceeded only by the 1,501,473 page views from the preceding year. Altogether, cumulative lifetime visitation to The Rational Argumentator’s pages has reached 13,933,800 and will surpass 14 million soon.  During its seventeenth year, TRA published 37 features; our rate of publication has slowed once again due to the whirlwind of activity within the United States Transhumanist Party / Transhuman Party (USTP), which is undergoing a turbulent primary election year and whose website published 123 features during the same time. However, our typical features during the past year have been in-depth and allow a thorough exploration of their subject matters.

We are pleased, furthermore, to have additional assistance and resources at our disposal. The work of TRA’s new Assistant Editor, Bobby Ridge, has enabled us to increase the pace of publication once again in recent months. Moreover, many of the highlights of the USTP’s efforts have been featured on TRA as well, allowing our readers to glimpse the many valuable activist initiatives that advocate technological progress and rational philosophy. My role as Chairman of the USTP, in which I am nearing the completion of my third year, has given me unprecedented opportunities to discuss technology, philosophy, and their impacts on politics to a worldwide audience. It is due to these activities that I was able to interview Ray Kurzweil on stage in September 2018 and co-host the Cyborg and Transhumanist Forum at the Nevada State Legislature in May 2019 – the first-ever official transhumanist event within a State legislature, which enabled a successful amendment to Nevada’s Assembly Bill 226 to remove the bill sponsor’s previously proposed prohibition against voluntary microchip implants. TRA has also featured two major academic papers that I was immensely pleased to get published: “The United States Transhumanist Party and the Politics of Abundance” (The Transhumanism Handbook, Springer Nature, July 2019) and “Empowering Human Musical Creation through Machines, Algorithms, and Artificial Intelligence” (INSAM Journal, Issue 2, July 2019). Furthermore, this has been a year of many constructive interviews, lively discussions and debates, and a successful visit to the Wellness and Longevity Seminar in Burbank, California, where I delivered my presentation, “Progress in the Politics of Abundance” and also hosted a U.S. Transhumanist Party discussion panel.

The U.S. Transhumanist Party has, in recent months, been applying lessons and models of creation which were refined within the pages of The Rational Argumentator for years. The USTP’s recent call for the development of free transhumanist symbols was a case in point. The non-monetary model of publication which TRA has employed since its founding has been readily scaled up to an entire non-monetary political organization, the USTP, whose projects are based on the skills and dedication of its volunteer Officers and members. By setting our sights high, guided by Reason and the desire for constructive improvement of the human condition, we can all work for a brighter future with greater enthusiasm and productivity – knowing that the results of our efforts will be directly available to others, indefinitely reproducible, and able to make concrete impacts upon the world. At times an extensive philosophical foundation, reinforced by continual study and deliberation, is needed to arrive at simple but powerful insights which, if applied, alter the dynamics of human behavior and set forth a new system of incentives where the desire to do good is itself prized.

The above explication of the value of non-monetary approaches is not intended, of course, to criticize monetary or capitalist systems in any way – but rather to highlight the importance of parallel and complementary systems of intellectual creation that do not rely on the kinds of rationing that scarcity of physical goods necessitates. Indeed, as more human creation has become possible in the digital realm, and as automation has made many physical processes far swifter and less expensive than previously, we are rapidly nearing a time when abundance, rather than scarcity, becomes the prevailing condition in terms of the availability of goods and concepts. The barrier to progress in those situations is the mindset that continues to cling to an assumption of pervasive scarcity when, in fact, positive-sum solutions exist which allow everyone to achieve their desired objectives and more besides.

While there remain major areas of scarcity to overcome – particularly the scarcity of time which limits us all and to transcend which it is imperative to achieve indefinite life extension – in many instances in today’s world scarcity is either artificially imposed (as in, for instance, monopolies on software or medical patents or exorbitant prices charged for access to some academic journal articles) or imagined (as in the numerous protectionist fallacies that pervade mainstream political discourse today). While it is difficult for humans to transcend the evolved mindsets which served our ancestors more effectively during epochs when scarcity was indeed ubiquitous and relegated most humans to the barest edges of survival, nonetheless the effort must be made to adapt our thinking to the material realities and technological possibilities of our time. We are not yet at the technological stage where the evolutionary baggage of fallacious thinking might be genetically engineered out of us, so, in the meantime, our best recourse is to exert a conscious effort to resist the traps and ruts of evolved conditioning and replace them with thorough, rational, intentional consideration of the evidence around us. The opportunities have never been greater to access a plethora of thought-provoking content that both trains and inspires the mind to pursue the rational approach instead of the evolved one. Will and time are the remaining ingredients needed for the rational approach to take root and flourish within the individual mind. However much time our readers are willing to spend on The Rational Argumentator’s pages, I am hopeful that all such time will incrementally cultivate elevated ways of thinking that will translate into world-improving action.

While there remain plentiful challenges to overcome in the contemporary culture of lowest-common-denominator discourse, there is also much to look forward to in the transformations that both technology and rational advocacy can bring about. Amidst all the difficulties, transhumanism and techno-optimism are rising in influence, and I have experienced this first-hand. I am confident that if the majority of the current problems facing humankind can be overcome in the next several decades, then any future problems that arise will be significantly less severe than the familiar predicaments of our world today. The Rational Argumentator will remain a freely available, frequently updated resource for those who seek intellectual sustenance and inspiration to fuel the attainment of the next, greatest-yet era of our civilization.

Gennady Stolyarov II,
Editor-in-Chief, The Rational Argumentator

This essay may be freely reproduced using the Creative Commons Attribution Share-Alike International 4.0 License, which requires that credit be given to the author, G. Stolyarov II. Find out about Mr. Stolyarov here.

The Rational Argumentator’s Sixteenth Anniversary Manifesto

The Rational Argumentator’s Sixteenth Anniversary Manifesto

The New Renaissance Hat
G. Stolyarov II
September 2, 2018
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On August 31, 2018, The Rational Argumentator completed its sixteenth year of publication. TRA is older than Facebook, YouTube, Twitter, and Reddit; it has outlasted Yahoo! Geocities, Associated Content, Helium, and most smaller online publications in philosophy, politics, and current events. Furthermore, the age of TRA now exceeds half of my lifetime to date. During this time, while the Internet and the external world shifted dramatically many times over, The Rational Argumentator strived to remain a bulwark of consistency – accepting growth in terms of improvement of infrastructure and accumulation of content, but not the tumultuous sweeping away of the old to ostensibly make room for the new. We do not look favorably upon tumultuous upheaval; the future may look radically different from the past and present, but ideally should be built in continuity with both, and with preservation of any beneficial aspects that can possibly be preserved.

The Rational Argumentator has experienced unprecedented visitation during its sixteenth year, receiving 1,501,473 total page views as compared to 1,087,149 total page views during its fifteenth year and 1,430,226 during its twelfth year, which had the highest visitation totals until now. Cumulative lifetime TRA visitation has reached 12,481,258 views. Even as TRA’s publication rate has slowed to 61 features during its sixteenth year – due to various time commitments, such as the work of the United States Transhumanist Party (which published 147 features on its website during the same timeframe) – the content of this magazine has drawn increasing interest. Readers, viewers, and listeners are gravitating toward both old and new features, as TRA generally aims to publish works of timeless relevance. The vaster our archive of content, the greater variety of works and perspectives it spans, the more issues it engages with and reflects upon – the more robust and diverse our audience becomes; the more insulated we become against the vicissitudes of the times and the fickle fluctuations of public sentiment and social-media fads.

None of the above is intended to deny or minimize the challenges faced by those seeking to articulate rational, nuanced, and sophisticated ideas on the contemporary Internet. Highly concerning changes to the consumption and availability of information have occurred over the course of this decade, including the following trends.

  • While social media have been beneficial in terms of rendering personal communication at a distance more viable, the fragmentation of social media and the movement away from the broader “open Internet” have seemingly accelerated. Instead of directly navigating and returning to websites of interest, most people now access content almost exclusively through social-media feeds. Even popular and appealing content may often become constrained within the walls of a particular social network or sub-group thereof, simply due to the “black-box” algorithms of that social network, which influence without explanation who sees what and when, and which may not be reflective of what those individuals would have preferred to see. The constantly changing nature of these algorithms renders it difficult for content creators to maintain steady connections with their audiences. If one adds to the mix the increasing and highly troubling tendency of social networks to actively police the content their members see, we may be returning to a situation where most people find their content inexplicably curated by “gatekeepers” who, in the name of objectivity and often with unconscious biases in play, often end up advancing ulterior agendas not in the users’ interests.
  • While the democratization of access to knowledge and information on the Internet has undoubtedly had numerous beneficial effects, we are also all faced with the problem of “information overload” and the need to prioritize essential bits information within an immense sea which we observe daily, hourly, and by the minute. The major drawback of this situation – in which everyone sees everything in a single feed, often curated by the aforementioned inexplicable algorithms – is the difficulty of even locating information that is more than a day old, as it typically becomes buried far down within the social-media feed. Potential counters exist to this tendency – namely, through the existence of old-fashioned, static websites which publish content that does not adjust and that is fixed to a particular URL, which could be bookmarked and visited time and again. But what proportion of the population has learned this technique of bookmarking and revisitation of older content – instead of simply focusing on the social-media feed of the moment? It is imperative to resist the short-termist tendencies that the design of contemporary social media seems to encourage, as indulging these tendencies has had deleterious impacts on attention spans in an entire epoch of human culture.
  • Undeniably, much interesting and creative content has proliferated on the Internet, with opportunities for both deliberate and serendipitous learning, discovery, and intellectual enrichment. Unfortunately, the emergence of such content has coincided with deleterious shifts in cultural norms away from the expectation of concerted, sequential focus (the only way that human minds can actually achieve at a high level) and toward incessant multi-tasking and the expectation of instantaneous response to any external stimulus, human or automated. The practice of dedicating a block of time to read an article, watch a video, or listen to an audio recording – once a commonplace behavior – has come to be a luxury for those who can wrest segments of time and space away from the whirlwind of external stimuli and impositions within which humans (irrespective of material resources or social position) are increasingly expected to spin. It is fine to engage with others and venture into digital common spaces occasionally or even frequently, but in order for such interactions to be productive, one has to have meaningful content to offer; the creation of such content necessarily requires time away from the commons and a reclamation of the concept of private, solitary focus to read, contemplate, apply, and create.
  • In an environment where the immediate, recent, and short-term-oriented content tends to attract the most attention, this amplifies the impulsive, range-of-the-moment, reactive emotional tendencies of individuals, rather than the thoughtful, long-term-oriented, constructive, rational tendencies. Accordingly, political and cultural discourse become reduced to bitter one-liners that exacerbate polarization, intentional misunderstanding of others, and toxicity of rhetoric. The social networks where this has been most salient have been those that limit the number of characters per post and prioritize quantity of posts over quality and the instantaneity of a response over its thoughtfulness. The infrastructures whose design presupposes that everyone’s expressions are of equal value have produced a reduction of discourse to the lowest common denominator, which is, indeed, quite low. Even major news outlets, where some quality selection is still practiced by the editors, have found that user comments often degenerate into a toxic morass. This is not intended to deny the value of user comments and interaction, in a properly civil and constructive context; nor is it intended to advocate any manner of censorship. Rather, this observation emphatically underscores the need for a return to long-form, static articles and longer written exchanges more generally as the desirable prevailing form of intellectual discourse. (More technologically intensive parallels to this long-form discourse would include long-form audio podcasts or video discussion panels where there is a single stream of conversation or narrative instead of a flurry of competing distractions.) Yes, this form of discourse takes more time and skill. Yes, this means that people have to form complex, coherent thoughts and express them in coherent, grammatically correct sentences. Yes, this means that fewer people will have the ability or inclination participate in that form of discourse. And yes, that may well be the point – because less of the toxicity will make its way completely through the structures which define long-form discourse – and because anyone who can competently learn the norms of long-form discourse, as they have existed throughout the centuries, will remain welcome to take part. Those who are not able or willing to participate can still benefit by spectating and, in the process, learning and developing their own skills.

The Internet was intended, by its early adopters and adherents of open Internet culture – including myself – to catalyze a new Age of Enlightenment through the free availability of information that would break down old prejudices and enable massively expanded awareness of reality and possibilities for improvement. Such a possibility remains, but humans thus far have fallen massively short of realizing it – because the will must be present to utilize constructively the abundance of available resources. Cultivating this will is no easy task; The Rational Argumentator has been pursuing it for sixteen years and will continue to do so. The effects are often subtle, indirect, long-term – more akin to the gradual drift of continents than the upward ascent of a rocket. And yet progress in technology, science, and medicine continues to occur. New art continues to be created; new treatises continue to be written. Some people do learn, and some people’s thinking does improve. There is no alternative except to continue to act in pursuit of a brighter future, and in the hope that others will pursue it as well – that, cumulatively, our efforts will be sufficient to avert the direst crises, make life incrementally safer, healthier, longer, and more comfortable, and, as a civilization, persist beyond the recent troubled times. The Rational Argumentator is a bulwark against the chaos – hopefully one among many – and hopefully many are at work constructing more bulwarks. Within the bulwarks, great creations may have room to develop and flourish – waiting for the right time, once the chaos subsides or is pacified by Reason, to emerge and beautify the world. In the meantime, enjoy all that can be found within our small bulwark, and visit it frequently to help it expand.

Gennady Stolyarov II,
Editor-in-Chief, The Rational Argumentator

This essay may be freely reproduced using the Creative Commons Attribution Share-Alike International 4.0 License, which requires that credit be given to the author, G. Stolyarov II. Find out about Mr. Stolyarov here.

The Rational Argumentator’s Fifteenth Anniversary Manifesto

The Rational Argumentator’s Fifteenth Anniversary Manifesto

The New Renaissance Hat
G. Stolyarov II
August 31, 2017
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As of today The Rational Argumentator has been in publication continuously for fifteen years – half of my lifetime to date. The more time passes, the more the value of continuity is reinforced for me, and so I hope that these fifteen years have only been an auspicious beginning for The Rational Argumentator. TRA shall continually endeavor to improve and expand in new directions, but always by building upon the old and by remaining rooted in a core identity – the championing of the principles of Reason, Rights, and Progress – the ideas that made Western civilization great. These ideals will hopefully be applied to forge a new global, universal human (and transhuman) civilization which we – all reasonable and decent people who wish to join this effort – can assemble by picking up the pieces of the wreckage of our unfortunate, downward-spiraling moment in history.

We live today in what Robert Heinlein prognosticated in his science fiction as the “Crazy Years”, which he described as exhibiting “Considerable technical advance during this period, accompanied by a gradual deterioration of mores, orientation, and social institutions” – gradual deterioration that became quite sudden and cataclysmic in 2016 and 2017. The climate of contemporary societies and political systems, particularly that of the United States, evokes William Butler Yeats’s famous lines:

  Things fall apart; the centre cannot hold;
Mere anarchy is loosed upon the world,
The blood-dimmed tide is loosed, and everywhere
The ceremony of innocence is drowned;
The best lack all conviction, while the worst
Are full of passionate intensity.

The deterioration cannot be attributed to any particular individual or even faction (these are, at most, symptoms), but rather to the fraying general fabric of contemporary Western, particularly American, life. Those who have regularly read the pages of The Rational Argumentator will not be surprised at my view that the deterioration is primarily due to the abandonment of upward aspiration both within mainstream culture and among various subcultures – a rejection of 18th-century Enlightenment meliorism and an embrace of postmodern aimlessness. To reverse this tendency, now, more than ever, it is essential to emphasize the importance of rational inquiry, civil discourse, and the mindset of building a civilization – as opposed to militant subjectivism (where a person considers his or her feelings to be unquestioned dogma – and woe to those who challenge them!), coarse crudity in manners, riotousness, and the mindset of “tearing down the system” in a futile attempt to start from scratch. We cannot and must not start over – for the primitive state of humankind is far worse than our admittedly deeply imperfect morass of institutions and norms. But we can – and we must – repair and build upon the achievements of the past, combining them with new technologies and insights to forge the next great era of our civilization, a project I outline briefly in a two-party video series, “The Great Transhumanist Game”.

Amid the turmoil, I was pleased to see that The Rational Argumentator has gained notice and achieved significant increases in its visitation, receiving 1,087,149 total page views during its fifteenth year, as compared to 823,968 page views the year prior. Cumulative lifetime TRA visitation stands at 10,979,785 page views, and I am confident that the 11-million mark will be exceeded in September 2017. Perhaps more readers are seeking an antidote to the Crazy Years. Reason is that antidote, and these pages provide it in abundance.

During its fifteenth year, TRA published 140 features. While this was a lower rate of publication than the 208 to 314 features published per year in the preceding five years, TRA has at the same time become allied with the United States Transhumanist Party, of which I became Chairman in November 2016. The U.S. Transhumanist Party website has been brimming with new content, contributed by a wide variety of forward-thinking minds, and I am proud that this young but steadily growing organization has published 105 features during my tenure as Chairman thus far. I am also proud of the cadre of volunteer Officers that the U.S. Transhumanist Party has assembled – a team of dedicated advocates for the future, which will hopefully greatly expand with time and become the core of a movement that will transform and redirect society and culture back toward the ideals of reason and amelioration.

Thus, for the upcoming year, I pose an ambitious task for The Rational Argumentator and its readers. Let us make sure that Yeats’s words remain a warning rather than the ever-present reality. The center must hold, and we must ensure that it holds. Each of us can participate in this project. We must become the center upon which human civilization depends for its survival, continuity, and growth. Through both great endeavors and small, routine maintenance tasks; through creation of elevated and noble works, as well as everyday kindnesses to the people in our lives; through the rhetoric that inspires great aspirations and the decorum that conveys respect and uplifts our sentiments into the realm of good will – we must be the agents of cultural transformation – a New Renaissance, a Re-Enlightenment, indeed, a Recivilization to follow the Crazy Years. One of my most inspired moments of the past year has been seeing the finished painting of the City of New Antideath, which I commissioned from artist Ekaterinya Vladinakova. I invite you to gaze upon this colossal cityscape to gain glimpses at an era where all of our major aims – the return of reason as the paradigm for life, the attainment of indefinite longevity, the liberation of humankind from privation and conflict – have been attained. May it inspire you to go forth and take the many necessary incremental steps toward such a world.

This essay may be freely reproduced using the Creative Commons Attribution Share-Alike International 4.0 License, which requires that credit be given to the author, G. Stolyarov II. Find out about Mr. Stolyarov here.

Activating Transhumanism – James Strole Interviews G. Stolyarov II on RAAD Fest

Activating Transhumanism – James Strole Interviews G. Stolyarov II on RAAD Fest

The New Renaissance Hat
G. Stolyarov II and James Strole
June 24, 2017
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U.S. Transhumanist Party Chairman Gennady Stolyarov II was interviewed by James Strole regarding the forthcoming RAAD Fest 2017 in San Diego, California, which will occur on August 9-13, 2017. This interview addressed Mr. Stolyarov’s impressions of RAAD Fest 2016, his goals for the transhumanist movement in politics, and how various perspectives within the transhumanist and life-extensionist movement can benefit from interfacing with one another. Watch the video of the interview on YouTube or below.

At RAAD Fest 2017, Mr. Stolyarov will be moderating a panel consisting of transhumanist philosophers, researchers, and activists – including Zoltan Istvan, Dr. Ben Goertzel, Dr. Max More, and Dr. Natasha Vita-More. You can see the full RAAD Fest schedule here.

The panel moderated by Mr. Stolyarov will occur at 10 a.m.  on Friday, August 11, 2017. Machine augmentation of human bodies and minds will be one topic of discussion; transhumanist politics will be another. As previously announced, Mr. Stolyarov will inaugurate the panel with a brief presentation entitled “The U.S. Transhumanist Party: Pursuing a Peaceful Political Revolution for Longevity”.

Members of the U.S. Transhumanist Party: When registering for RAAD Fest, you can use the special discount code TRANSHUMAN, which will now reduce the cost of registration to $497.

U.S. Transhumanist Party Support for H.R. 1868, the Restoring American Privacy Act of 2017 – Post by G. Stolyarov II

U.S. Transhumanist Party Support for H.R. 1868, the Restoring American Privacy Act of 2017 – Post by G. Stolyarov II

The New Renaissance HatG. Stolyarov II
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The United States Transhumanist Party and Nevada Transhumanist Party support H.R. 1868, the Restoring American Privacy Act of 2017, proposed by Rep. Jacky Rosen of Henderson, Nevada.

This bill, if enacted into law, would undo the power recently granted by S.J. Res. 34 for regional-monopoly Internet Service Providers (ISPs) to sell individuals’ private data – including browsing histories – without those individuals’ consent. For more details, read Caleb Chen’s article on Privacy News Online, “Congresswoman Rosen introduces Restoring American Privacy Act of 2017 to reverse S.J. Res. 34”.

Section I of the U.S. Transhumanist Party Platform states, “The United States Transhumanist Party strongly supports individual privacy and liberty over how to apply technology to one’s personal life. The United States Transhumanist Party holds that each individual should remain completely sovereign in the choice to disclose or not disclose personal activities, preferences, and beliefs within the public sphere. As such, the United States Transhumanist Party opposes all forms of mass surveillance and any intrusion by governmental or private institutions upon non-coercive activities that an individual has chosen to retain within his, her, or its private sphere. However, the United States Transhumanist Party also recognizes that no individuals should be protected from peaceful criticism of any matters that those individuals have chosen to disclose within the sphere of public knowledge and discourse.”

Neither governmental nor private institutions – especially private institutions with coercive monopoly powers granted to them by laws barring or limiting competition – should be permitted to deprive individuals of the choice over whether or not to disclose their personal information.

Individuals’ ownership over their own data and sovereignty over whether or not to disclose any browsing history or other history of online visitation to external entities are essential components of privacy, and we applaud Representative Rosen for her efforts to restore these concepts within United States federal law.

Become a member of the U.S. Transhumanist Party for free  by filling out the membership application form here

Fundraiser by Lifespan.io & CellAge: Targeting Senescent Cells With Synthetic Biology

Fundraiser by Lifespan.io & CellAge: Targeting Senescent Cells With Synthetic Biology

The New Renaissance HatCellAge
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Editor’s Note: The Rational Argumentator and the U.S. Transhumanist Party support Lifespan.io and CellAge in their work towards groundbreaking scientific life-extension research. Finding a way to repair age-related damage to senescent cells would be a fundamental breakthrough for transhumanism, and we offer our best wishes and support for those striving towards these new technologies.

               ~ Gennady Stolyarov II, Editor-in-Chief, The Rational Argumentator, December 11, 2016

From Lifespan.io and CellAge:

Our society has never aged more rapidly – one of the most visible symptoms of the changing demographics is the exponential increase in the incidence of age-related diseases, including cancer, cardiovascular diseases and osteoarthritis. Not only does aging have a negative effect on the quality of life among the elderly but it also causes a significant financial strain on both private and public sectors. As the proportion of older people is increasing so is health care spending. According to a WHO analysis, the annual number of new cancer cases is projected to rise to 17 million by 2020, and reach 27 million by 2030. Similar trends are clearly visible in other age-related diseases such as cardiovascular disease. Few effective treatments addressing these challenges are currently available and most of them focus on a single disease rather than adopting a more holistic approach to aging.

Recently a new approach which has the potential of significantly alleviating these problems has been validated by a number of in vivo and in vitro studies. It has been demonstrated that senescent cells (cells which have ceased to replicate due to stress or replicative capacity exhaustion) are linked to many age-related diseases. Furthermore, removing senescent cells from mice has been recently shown to drastically increase mouse healthspan (a period of life free of serious diseases).

Here at CellAge we are working hard to help translate these findings into humans!

CellAge, together with a leading synthetic biology partner, Synpromics, are poised to develop a technology allowing for the identification and removal of harmful senescent cells. Our breakthrough technology will benefit both the scientific community and the general public.

In short, CellAge is going to develop synthetic promoters which are specific to senescent cells, as promoters that are currently being used to track senescent cells are simply not good enough to be used in therapies. The most prominently used p16 gene promoter has a number of limitations, for example. First, it is involved in cell cycle regulation, which poses a danger in targeting cells which are not diving but not senescent either, such as quiescent stem cells. Second, organism-wide administration of gene therapy might at present be too dangerous. This means senescent cells only in specific organs might need to be targeted and p16 promoter does not provide this level of specificity. Third, the p16 promoter is not active in all senescent cells. Thus, after therapies utilizing this promoter, a proportion of senescent cells would still remain. Moreover, the p16 promoter is relatively large (2.1kb), making it difficult to incorporate in present gene therapy vehicles. Lastly, to achieve the intended therapeutic effect the strength of p16 promoter to drive therapeutic effect might not be high enough.

CellAge will be constructing a synthetic promoter which has a potential to overcome all of the mentioned limitations. A number of gene therapy companies, including uniQure, AGTC and Avalanche Biotech have successfully targeted other types of cells using this technology. With your help, we will be able to use same technology to develop tools and therapies for accurate senescent cell targeting.

The Rational Argumentator’s Fourteenth Anniversary Manifesto: Who Is the Western Man?

The Rational Argumentator’s Fourteenth Anniversary Manifesto: Who Is the Western Man?

The New Renaissance Hat
G. Stolyarov II
August 31, 2016
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Who Is the Western Man?

On the fourteenth anniversary of The Rational Argumentator, it is fitting to consider the tagline that has been featured on TRA since its founding: “A Journal for Western Man”. But who is this Western Man for whom The Rational Argumentator is intended? In 2002, the answer to that question seemed rather apparent for at least a substantial segment of then-prevalent libertarian, conservative, and Objectivist thinkers who, each in their own way, understood the Western Man to stand for the general cultural ideals and noblest aspirations of Western civilization.

Unfortunately, the decade of the 2010s and the past two years especially have seen the rise of a noxious and fundamentally anti-Western, anti-modern, and anti-civilization movement known as the “alt-right”, which has attempted to appropriate the rhetoric of Western culture and even of the Renaissance for itself. The Rational Argumentator will not allow this appropriation to remain unchallenged. TRA stands resolutely in opposition to all forms of bigotry, racism, nativism, misogyny, and any other circumstantially rooted intolerance – all of which are contrary to the ideals of high Western civilization. But at the same time, The Rational Argumentator also cannot cave to the “social justice” campus activism of the far Left, which would have even the very identification of Western culture and civilization banished, lest it offend the ever-more-delicate sensibilities of firebrand youths who resolutely refuse to let knowledge of the external world get in the way of their “feelings” and subjective experiences. TRA will not abandon the Western Man, but will continue to explain what it is that the Western Man represents and why these principles are more important and enduring than any tumultuous, ephemeral, and most likely futile and self-defeating activist movements of our era.

So who is the Western Man? It is a not a particular man from the West. It is not a descriptor limited to a particular subset of individuals based on their birth, skin color, national origin, or even gender. Indeed, my original intent behind the “Western Man” descriptor was specifically to salvage the generic term “man” – meaning an archetypical representative of humankind – from any suggestions that it must necessarily be gender-specific. This subtitle was meant transparently to imply, “Of course, ‘Western Man’ includes women, too!”  Some of the greatest and most courageous Western Men – from Hypatia of Alexandria to Mary Wollstonecraft to Ayn Rand to Ayaan Hirsi Ali – have been women.

A Western Man can have been born anywhere, have any physical features, any age, any gender (or lack of gender identity), any sexual preferences (or lack thereof), any religion (or lack thereof) – as long as he/she/it is a thinking being who accepts the valuable contributions of Western culture and civilization and seeks to build upon them. If self-aware, rational artificial intelligences are developed in the future, or if an intelligent alien species comes into contact with us, these beings could potentially be Western Men as well.

A Western Man will respect and seek to learn from the great philosophy, literature, art, music, natural and social sciences, mathematics, and political theory that flourished in Western societies throughout the past three millennia – although by no means is a Western man required to focus exclusively on ideas that originated in the West. Indeed, Western culture itself has unceasingly interacted with and absorbed the intellectual contributions of Egyptian, Mesopotamian, Arabic, Persian, Indian, Chinese, Korean, and Japanese thinkers and creators – to provide just a few examples. Likewise, a great deal of hope for the future of Western civilization can be found among entrepreneurs in Asia, Africa, and Latin America who have endeavored, with notable success, to spread the technologies of the digital age, construct great buildings, and lift billions of people out of abject poverty and into humane and respectable living standards accompanied by ever-increasing longevity.

A Western Man is someone who embraces the ideal of cosmopolitan universalism – a rejection of circumstantially defined tribalism, of the casting of people as “one of us” or “the other” based on attributes that they did not choose. This cosmopolitan universalism is the product of both a long-evolving philosophical framework and the material abundance that enabled the broadening of what Adam Smith termed our circles of sympathy to encompass ever more people.

The edifice of Western philosophical thought has been built upon by thinkers since the times of Thales, Socrates, and Aristotle – but its greatest intellectual breakthroughs were made during the 18th-century Age of Enlightenment. The Western Men who embraced these ideals were often personally flawed; they were men of their time and constrained by the practical realities and social mores that surrounded them. Some Western Men throughout history have, unfortunately, owned slaves, respected individual liberty only in some instances, or been improperly prejudiced against broad groups of people due to ignorance or gaps in the consistent application of their principles. Nonetheless, the legacy of their work – the notions of universal, inalienable individual rights and the preciousness of each person’s liberty and humanity – has been indispensable for later accomplishments, such as the abolition of slavery, women’s suffrage and liberation, civil and privacy rights, cultural and legal acceptance of homosexuality, and recognition of individual rights for members of religious minorities, atheists, and children. If we are able to see farther and know better than to repeat some of the moral errors of the past, it is because, to paraphrase Sir Isaac Newton, we stand on the shoulders of intellectual giants who paved the way for our embrace of the aforementioned great cultural achievements.

The ideals of peaceful commerce and cultural exchange – indeed, cultural appropriation (in an educated, informed, and deliberate manner) of the best elements of every time, place, and way of life – have resulted in a dramatic reduction in warfare, a general decline in nationalistic and tribal hatreds, and a widespread understanding of the essential humanity of our fellows in all parts of the world. Were it not for the intellectual achievements of Western civilization and the global commercial and industrial networks to which it gave rise, humankind would still be embroiled in a bitter, Hobbesian war of all against all. A Western Man is anyone who gives the essential achievements of modernity their well-deserved recognition and admiration, and who studies and offers justified respect to the forebears and authors of these achievements. A Western Man is also anyone who seeks to build upon these accomplishments and add his, her, or its distinctive bricks to the edifice of human progress.

A Western Man is not a fanatic or a bully, and sees fanatics and bullies as the threats to civilization that they are. A Western Man does not use ideology to stifle peaceful expression or compel others to dutifully “know their place” within some would-be totalitarian static social order. A Western Man knows that some people will disagree with him, her, or it, and they have the right to disagree peacefully. However, they do not have the right to be protected from attempts at persuasion or the presentation of diverse and possibly contrary views.

A Western Man embraces reason as the way to discover more about the external world and about human beings. Reason is not the exclusive province of any subset of people; anyone is capable of it, but it takes training and effort – and great respect for the intellect – to utilize consistently and properly. From reason stem the empirical scientific method, the deductive processes of formal logic and mathematics, and the application of empirical and logical truths to the development of technology which improves the human condition. A Western Man does not vilify technology, but rather sees it as a key driver of human progress and an enabler of moral growth by giving people the time and space which prosperity affords, making possible contemplation of better ways of living and relating to others – a prerogative only available to those liberated from hand-to-mouth subsistence.

The ideal of the Western Man is to maintain the great things which have already been brought into this world, and to create new achievements that further improve human life. There is thus both a conservative and a progressive motive within the Western Man, and they must combine to sustain a rich and vital civilization. A Western Man can go by labels such as “liberal”, “conservative”, “libertarian”, “progressive”, or “apolitical” – as long as they are accompanied by careful thought, study, discernment, work ethic, and an earnest desire to build what is good instead of, out of rage or spite, tearing down whatever exists. Conservation of great achievements and progress in creating new achievements are not antagonists, but rather part of the same essential mode of functioning of the Western Man – transcending petty and often false political antagonisms which needlessly create acrimony among people who should all be working to take civilization to the next level.

The next level of civilization – the unceasing expansion of human potential – is the preoccupation of the Western Man. This – not descending into contrived identitarian antagonisms – is the great project of our era. Building on the philosophical groundwork laid by Enlightenment humanism and its derivatives, a Western Man can explore the next stage of intellectual evolution – that of transhumanism, which promises to liberate humankind from its age-old shackles of death, disease, severe scarcity, Earth-boundedness, and internecine conflict.

Who is the Western Man? If you accept the challenge and the honor of supporting and building upon the great civilization which offers us unparalleled opportunities to create a glorious future for all – then the Western Man can be you.

TRA Statistics and Achievements During Its Fourteenth Year

TRA published 211 regular features during its fourteenth year, a rate of publication comparable to that of the eleventh and thirteenth years, while remaining below the extremely active tenth and twelfth years, as shown in the table below:

TRA Year Regular Features Published Page Views in Year
10th 306 1,302,774
11th 208 1,077,192
12th 314 1,430,226
13th 228 892,082
14th 211 823,968

With slightly less content published during the fourteenth year, and a similar average number of page views per published feature (3,905.06 in the fourteenth year versus 3,912.64 in the thirteenth year), it could be expected that total page views would decline slightly. While TRA did not reach the milestone of 10,000,000 cumulative page views during its fourteenth year, it did come the overwhelming majority of the way toward it. Total lifetime TRA visitation currently stands at 9,892,636 page views. However, I am confident that the 10-million page-view threshold will be exceeded within the next two months.

I have reason to expect that publication activity will again accelerate during TRA’s fifteenth year, although this may not occur immediately. Over the past year, I have been occupied with satisfying some of the last remaining requirements of my actuarial studies, and their successful completion is in sight. In the meantime, I collaborated with ACTEX Publications to produce a major 400-page commercial study guide, Practice Problems in Advanced Topics in General Insurance, for SOA Exam GIADV.

Several large-scale endeavors within the transhumanist and life-extensionist movements were pursued over the past year. TRA’s anniversary (August 31) coincides with the date of formation of the Nevada Transhumanist Party, a non-election-oriented, non-donation-accepting, policy-oriented party that advocates for the widespread adoption of emerging technologies, individual liberty, and the pursuit of indefinite life extension. The Nevada Transhumanist Party has grown to 107 members during its first year and has been a forum for numerous thought-provoking discussions. Nevada Transhumanist Party activities have occurred online via its Facebook page and its hosted video panels, such as the Panel Discussion on Hereditary Religion, a conversation among Transhumanist Libertarians and Socialists, and the panel for International Longevity Day, in collaboration with MILE – the Movement for Indefinite Life Extension – entitled “How Can Life Extension Become as Popular as the War on Cancer?” In-person activities of the Nevada Transhumanist Party included attendance at a university political lecture, a local Libertarian candidate’s campaign event, and RAAD Fest, the largest in-person gathering of life-extension supporters to date, where I personally met and spoke with such luminaries of the life-extension movement as Aubrey de Grey, Bill Andrews, and Zoltan Istvan.

Gradual but fundamental shifts are occurring that will contribute to more frequent and impactful activity on The Rational Argumentator’s pages during its fifteenth year. As the overview of the Western Man in this manifesto indicates, the importance of TRA’s work and ideals remains paramount. TRA will remain a bulwark of thoughtful consistency in an era where it seems entire societies have become unmoored from core principles that are integral to a successful civilization. We will steadfastly champion the virtues of reason and deliberation, discussion and civil debate, individualism and classical liberal tolerance, creation and maintenance. Even when the tumult of current events calls into question the foundations of civilized life, TRA will be here to reaffirm and uphold them.

This essay may be freely reproduced using the Creative Commons Attribution Share-Alike International 4.0 License, which requires that credit be given to the author, G. Stolyarov II. Find out about Mr. Stolyarov here.

G. Stolyarov II Interviews Demian Zivkovic Regarding the D.N.A. – Gene Therapies Congress

G. Stolyarov II Interviews Demian Zivkovic Regarding the D.N.A. – Gene Therapies Congress

The New Renaissance Hat
G. Stolyarov II and Demian Zivkovic
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Mr. Stolyarov invited Demian Zivkovic, President of the Institute of Exponential Sciences (IES), to discuss the forthcoming Designing New Advances (D.N.A.) Gene Therapies Congress in Utrecht, The Netherlands.

The interview took place on Sunday, June 19, 2016, at 11 a.m. US Pacific Time. Watch the recording here.

The D.N.A. Congress is scheduled to occur on July 9, 2016, and will feature speakers such as Oliver Medvedik, Aubrey de Grey, Elizabeth Parrish, Keith Comito, and Tatjana Kochetkova. This event receives the strong endorsement of both The Rational Argumentator and the Nevada Transhumanist Party.

Read the announcement of the D. N. A. Congress here.

Contribute to the fundraiser for the D. N. A. Congress on Indiegogo  and Generosity.

DNA_Interview_CoverDemian Zivkovic is the president of the Institute of Exponential Sciences  (Facebook  / Meetup) – an international transhumanist think tank / education institute comprised of a group of transhumanism-oriented scientists, professionals, students, journalists, and entrepreneurs interested in the interdisciplinary approach to advancing exponential technologies and promoting techno-positive thought. He is also an entrepreneur and student of artificial intelligence and innovation sciences and management at the University of Utrecht.

Demian and the IES have been involved in several endeavors, such as organizing lectures on exponential sciences, interviewing experts such as Aubrey de Grey, joining several of Mr. Stolyarov’s futurism panels, and spreading Death is Wrong – Mr. Stolyarov’s illustrated children’s book on indefinite life extension – in The Netherlands.

Demian Zivkovic is a strong proponent of healthy life extension and cognitive augmentation. His interests include hyperreality, morphological freedom advocacy, postgenderism, and hypermodernism. He is currently working on his ambition of raising enough capital to make a real difference in life extension and transhumanist thought.

D.N.A. Congress Announcement by the Institute of Exponential Sciences

D.N.A. Congress Announcement by the Institute of Exponential Sciences

The New Renaissance HatInstitute of Exponential Sciences
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Editor’s Note: The forthcoming D.N.A. Congress in Utrecht, The Netherlands, hosted by the Institute of Exponential Sciences, devoted to discussions of gene therapies, receives the strong endorsement of both The Rational Argumentator and the Nevada Transhumanist Party. The D.N.A. Congress offers a promising venue to discuss the potential for gene therapies to cure diseases, lengthen lifespans, and improve quality of life for millions of people in the coming years and decades.

~ Gennady Stolyarov II, Editor-in-Chief, The Rational Argumentator, June 5, 2016

D.N.A CONGRESS PRESS RELEASE:

The Institute of Exponential Sciences (IES) has a large announcement to make. We are organising D.N.A – The largest European congress on human gene therapies, featuring speakers such as Aubrey de Grey, Liz Parrish, Oliver Medvedik and others.

Our event has been endorsed by LEAF, Heales VZW, BioViva, SENS Research Foundation, Singularity Network, People Unlimited, The Rational Argumentator, and many others. The event will be covered by national media and will be broadcasted online.

To make this vision a reality, we need your support. Share this message and donate today. Thank you!

IES needs your support to help make this vision a reality. Click here to donate to our crowdfunding campaign.

D.N.A – Designing New Advances: The second large Institute of Exponential Sciences event is coming to Utrecht

 

DNADemian Zivkovic

Utrecht – After a successful event last year in May, the grand congress is ready for a second edition. With a new name, we hope to make exponential sciences more approachable to the general public and bring people in the field closer together. The Institute of Exponential Sciences congress 2016 will be held at RASA podium on the 9th of July. The main theme of the event is gene therapies and cutting-edge applications of such therapies, such as health extension and interventions against human aging. To guarantee a great event, we have invited some of the biggest names in the field. Our guest speakers will be as follows:

Opening the event will be Oliver Medvedik, Ph.D, director of scientific programs at Genspace. Dr. Medvedik has earned his Ph.D at Harvard Medical school in the biomedical and biological sciences program. Since graduating from Harvard, he has worked as a biotechnology consultant, taught molecular biology to numerous undergraduates at Harvard, and mentored two of Harvard’s teams for the international genetically engineered machines competition (IGEM) held annually at M.I.T.

Our second speaker is Aubrey David Nicholas Jasper de Grey, Ph.D, an English author, Chief Science Officer of the SENS Research Foundation, and editor-in-chief of the academic journal Rejuvenation Research. Aubrey de Grey is well known for his focus on regenerative medicine and views on human aging. He will take the stage talking about the applications of current and upcoming technologies and studies which hold the potential to greatly extend our healthy lifespan.

Our third speaker is Tatjana Kochetkova, Ph.D, who is a fellow of the Institute of Exponential Sciences and a bioethicist. Dr. Kochetkova will follow up discussing the ethical and philosophical side of the technology and will address questions of what exponential technologies in biotech mean for society.

Our fourth speaker is Elizabeth Parrish, a fellow of the Institute of Exponential Sciences and the Founder and CEO of BioViva Sciences Inc, a Delaware corporation based in Seattle, WA, with labs and participating clinics in South/Central America where the majority of practical work is carried out. BioViva has been noted for being the first corporation in the world to treat a patient with gene therapy to reverse aging. The woman who wants to genetically engineer you will cover the basics of BioViva’s approach and vision for the the future, as well as the potential that gene therapies hold for radically improving our health and lives in the future.

Our fifth speaker will be Keith Comito, who is the founder and president of the Life Extension Advocacy Foundation (LEAF), a 501(c)(3) non-profit organization and a partner of the Institute of Exponential Sciences. Through LEAF, he operates the crowdfunding platform Lifespan.io, which supports biomedical research aimed at extending healthy human lifespan. He also serves as policy coordinator for the Global Healthspan Policy Institute, which facilitates relationships between researchers and government to advance initiatives in support of healthy life extension.

About Institute of Exponential Sciences

The Institute of Exponential Sciences is an international innovation-oriented think tank, outreach organisation, and networking platform based in the Netherlands, in the city of Utrecht. Its main activities include organising lectures and conferences, providing quality consultancy on innovation and exponential technologies, and collaborating with student organisations and universities in educating the public on the importance of exponential technologies.

It was founded by members of its predecessor, the Arma’thwynn society, which was a student group of like-minded young academics in the Netherlands. After organising events and attracting a very diverse and professional team of entrepreneurs, academics, and journalists, the society decided to move past student politics and make the move towards professionalism.

The Institute of Exponential Sciences is the result of that decision. After organising successful events (the largest of which was their symposium in April, 2015), the Institute of Exponential Sciences formalised its mission and reached out towards a process of international collaboration with other entities which share a techno-positive vision. The institute strives towards excellence in providing the best information and resources related to the issues relevant in the rapidly advancing technological society we live in.

The IES approach is focused on providing interdisciplinary education in the fields of exponential technologies such as artificial intelligence, bio-informatics, gene therapies, 3D-printing, augmented reality, and neural interfacing. We also provide a networking platform which allows entrepreneurs, scientists, journalists, and students to get in touch with others with similar ideas so that they may create the technologies of tomorrow. The IES strives not only to improve the speed of development of these technologies, but also to show the public the amazing possibilities technology provides for society.

IES and the IES logo are either registered trademarks or trademarks of IES Foundation in the Netherlands and/or other countries. All other products and/or services referenced are trademarks of their respective entities.