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G. Stolyarov II and xpallodoc Discuss the Future – Video Interview

G. Stolyarov II and xpallodoc Discuss the Future – Video Interview

On November 30, 2014, Mr. Stolyarov was interviewed by YouTube user xpallodoc, and the wide-ranging discussion encompassed subjects from visions of the future, indefinite life extension and the concept of I-ness, the future of money and economies, technological progress, virtual worlds, political barriers to progress, artificial intelligence, marriage and family, and being part of the push toward radical abundance and technological breakthroughs within our lifetimes.

References
– “Individual Empowerment through Emerging Technologies: Virtual Tools for a Better Physical World” – Video by G. Stolyarov II
– “How Can I Live Forever?: What Does and Does Not Preserve the Self” – Video by G. Stolyarov II

Why Do We Advocate for Rejuvenation Research? – Article by Reason

Why Do We Advocate for Rejuvenation Research? – Article by Reason

The New Renaissance Hat
Reason
November 24, 2014
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Yesterday, I had occasion to spend six hours or so in the emergency room of a medical center largely focused on treating serious conditions that are most prevalent in old people. A part of that experience by necessity involved listening to the comings, goings, and conversations of those present. These are not private places: they are typically divided visually by screens but with no way to avoid overhearing the staff and patients. The people there are generally not too concerned about privacy in the immediate sense in any case, having far more pressing matters to focus upon.

So, by proxy, one gets to experience small and somewhat wrenching slices of other people’s lives. It is very easy for even those who follow aging research and speak up for rejuvenation treatments to forget just how hard it is to be very old. It’s one thing to know about the catalog of pain, suffering, and loss of capabilities, the conditions we’d like to find ways to turn back, and another to watch it in action. It is, really, a terrible thing to be frail.

A fellow was brought in a little while after I arrived, a 90-something man who looked a lot better on the exterior than perhaps your mental picture of a 90-something individual might be. Tall, and surprisingly lacking in wrinkles stretched out on the rolling gurney under blankets, a mess of cables, and an oxygen mask. That he had fallen was what I heard from the conversation of the medics, and was in pain. He cried out several times as he was moved from the gurney. It took some time and care to do it without hurting him more, given his weakness.

He seemed confused at first, but that was just my misperception: you try being 90 and in pain some time and see how well you do while you’re being moved around and told to hold this and let go of that. The fellow answered the bevy of questions the receiving staff had for him, but the thing that caught at me was the time he took with the answers, and the questions he just missed. He was coherent, even quite sharp at times, not on any more painkillers than a handful of Tylenol, as I later heard, but he clearly struggled with something that we younger folk all take for granted: parse the question, find the information, form up a reply and speak it. Cognitive ability in all these areas becomes ever less efficient with old age, and there’s something hollowing about hearing what is clearly a capable guy set back for a dozen seconds by a short question about one of the details of his fall. The medic repeated the question a few times and in different ways, which was clearly just making the information overload worse.

It sticks with you to be the observer in this situation and clearly and suddenly realize that one day that faltering older person will be you, trying and often failing to force your mind into the necessary connections rapidly enough for the younger people around you. I know this, but knowing it and having it reinforced by being there are two very different things. An aged person is no less intelligent, far more experienced, wiser and all the rest, but the damage to the structure of the brain that occurs even in those without dementia means that making use of all of that in the way it deserves is near insurmountable.

The fellow’s 60-something daughter arrived a little later to provide support and fill in more of the details. A story was conveyed in bits and pieces: that he was near blind now, and just about too frail to walk safely, even with a frame. The blindness explained a great deal of what had sounded to my ignorant ears as confusion in the earlier part of the fellow’s arrival: we assume all too many things about those around us, such as the use of sight in an unfamiliar environment, or the ability to walk, or think quickly – and all of this is taken from us by aging. The fellow lived with his wife still, and she was of a similar age to him. His wife was not there because she herself was too frail to be undertaking even a short trip at such short notice. That seemed to me a harsh blow on top of the rest of what old age does to you. At some point you simply cannot do everything you’d want to as a partner. You are on the sidelines and at the point at which your other half is most likely to die, you are most likely unable to be there.

In this case the fellow was in no immediate danger by the sound of it. By good luck this was in no way likely to be a fatal accident, but rather another painful indignity to be endured as a part of the downward spiral of health and ability at the end of life. Once you get to the point at which simply moving from room to room bears a high risk of accident, and this is by no means unusual for a mentally capable person in their 90s, then it really is just a matter of time before you cannot live for yourself with only minimal assistance.

When talking with his daughter while he waited on a doctor and medical assistants to come and go with tests and updates, the fellow was much faster in his responses, though this was interrupted by a series of well-meaning but futile attempts to ease his pain by changing his position, each as much an ordeal as the move from the gurney had been. The conversation between father and daughter had the sense of signposts on well-worn paths, short exchanges that recapitulated the high points of many discussions that had come before. She wanted her father to move into an assisted living facility, and this fall was the latest in a line of examples as to why it was past the time for this – she simply could not provide all of the support needed on her own. She wasn’t even strong enough herself to be able to safely get him back up on his feet after a fall. He was concerned about cost and the difficulties of moving, uncertainties and change. They went back and forth on this for a while. “We have to accept that it’s just going to be more expensive as we get older,” she said at one point, and he replied “I think you’re getting the picture now,” and laughed. There wasn’t much to laugh about, but we can all do it here and there under these circumstances. I believe it helps.

I walked out of there after my six hours of hurry up and wait was done. They were still there, and whenever it is he leaves to go home it is unlikely it will be on his own two feet. But this is a scene I’ll no doubt be revisiting at some point in the future, some decades from now, playing the other role in this small slice of life. What comes around goes around, but I’d like it to be different for me, and more importantly to be different for millions of others a lot sooner than my old age arrives.

Which leads to this: why does Fight Aging! exist? Why do we do this? Why advocate, why raise funds for research programs into ways to treat aging that may take decades to pay off? We do this because we can help to create a future in which there will be no more emergency rooms like the one I visited, no conversations about increasing disability, no pain, and no struggles to answer questions as quickly as one used to. No profound frailty. All these things will be removed by the advent of therapies that can effectively repair the causes of aging, curing and preventing frailty and age-related disease, and the sooner this happens the more people will be spared.

Reason is the founder of The Longevity Meme (now Fight Aging!). He saw the need for The Longevity Meme in late 2000, after spending a number of years searching for the most useful contribution he could make to the future of healthy life extension. When not advancing the Longevity Meme or Fight Aging!, Reason works as a technologist in a variety of industries. 
***

This work is reproduced here in accord with a Creative Commons Attribution license. It was originally published on FightAging.org.

Rational Happiness, Op. 45 (2005) – Musical Composition and Video by G. Stolyarov II

Rational Happiness, Op. 45 (2005) – Musical Composition and Video by G. Stolyarov II

The New Renaissance Hat
G. Stolyarov II
November 2, 2014
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This 2005 piano composition by Mr. Stolyarov is a brief, structured, joyful work, which demonstrates how one might go about celebrating life in a rational fashion.

This work was remastered using the SynthFont2 software, with the Evanescence 2 and GMR Basico 1.1 instrument packs.

Download the MP3 file of this composition here.

See the index of Mr. Stolyarov’s compositions, all available for free download, here.

The artwork is Mr. Stolyarov’s Abstract Orderism Fractal 62, available for download here and here.

Remember to LIKE, FAVORITE, and SHARE this video in order to spread rational high culture to others.

Mr. Stolyarov’s “Dance of Reason, Op. 11”, Remastered by Prince Avery

Mr. Stolyarov’s “Dance of Reason, Op. 11”, Remastered by Prince Avery

The New Renaissance Hat
G. Stolyarov II and Prince Avery
October 26, 2014
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Note from Mr. Stolyarov: One of the wonderful aspects of a Creative Commons license is that it enables the talents of others to take an artist’s work in new directions. Here is a wonderfully remastered version of my 2002 composition, Dance of Reason, Op. 11, by Prince Avery, done using the FL Studio software and the Nexus plugin. The MP3 file of this rendition can be downloaded here or via the embedded player below.

Dance of Reason, Op. 11 (2002) – Musical Composition and Video by G. Stolyarov II

Dance of Reason, Op. 11 (2002) – Musical Composition and Video by G. Stolyarov II

The New Renaissance Hat
G. Stolyarov II
October 26, 2014
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This short piece for harpischord was composed by Mr. Stolyarov in 2002 and evokes the spirit of the Age of Enlightenment, an era whose esthetic combined elegance and ornateness with rationality and directedness.

This work was remastered using the SynthFont2 software, with the Evanescence 2 and GMR Basico 1.1 instrument packs.

Download the MP3 file of this composition here.

See the index of Mr. Stolyarov’s compositions, all available for free download, here.

The artwork is the “Concert Room of Sanssouci Palace, Potsdam, Germany”, painted by Eduard Gaertner in 1852 and accessible as a public-domain image here.

Remember to LIKE, FAVORITE, and SHARE this video in order to spread rational high culture to others.

The 2014 Fight Aging! Fundraiser Starts Now: We’ll Match Your Research Donations with $2 for Every $1 Given – Article by Reason

The 2014 Fight Aging! Fundraiser Starts Now: We’ll Match Your Research Donations with $2 for Every $1 Given – Article by Reason

The New Renaissance Hat
Reason
October 4, 2014
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Note from the Editor: The Rational Argumentator strongly supports this matching fundraiser and encourages all readers to donate any sums of money to the SENS Research Foundation, in order to accelerate the basic research into and the development of cures for the debilitating diseases of old age. I personally made a donation of $100 on October 4, 2014, knowing that its impact will be tripled through a 2-for-1 additional contribution by the generous donors who established the matching fund. This is the time to leverage our resources and ensure that this literally vital research gets done as soon as possible. I am grateful to Reason of FightAging.org for his tireless efforts in advocating for life-extension research and spearheading campaigns to attract the funding that this area of science urgently needs.

~ Gennady Stolyarov II, Editor-in-Chief, The Rational Argumentator, October 4, 2014

***

It is that time again, and our 2014 matching fundraiser started October 1st 2014. From now until the end of the year, December 31st 2014, we will match the first $50,000 donated to the SENS Research Foundation with $2 for every $1 given. These funds will help to speed progress in ongoing scientific programs conducted in US and European research centers, their ultimate aim being to repair and reverse the causes of frailty and age-related disease.

The SENS Research Foundation is a 501(c)(3) charity and all US donations are tax-deductible. Donations from most European Union countries are also tax-deductible, though the details vary by location. Please contact the SENS Research Foundation to find out more.

The Matching Fund Founders Ask You to Join Us

Who are we? We are Christophe and Dominique Cornuejols, David Gobel of the Methuselah Foundation, Dennis Towne, Håkon Karlsen, philanthropist Jason Hope, Michael Achey, Michael Cooper, and Reason of Fight Aging! We are all long-time supporters of SENS research aimed at rejuvenation through repair of the known root causes of aging. The few types of cellular and molecular damage that accumulate in all of our tissues cause progressive dysfunction and eventual death for everyone – unless something is done to stop it. This cause is important enough for everyone to do their part, and for us that means putting up a $100,000 matching fund we want you to help draw down: for every dollar you donate, we will match it with two of our own.

Even Small Donations Make a Meaningful Difference

Early stage medical biotechnology research of the sort carried out at the SENS Research Foundation costs little nowadays in comparison to the recent past. The cost of tools and techniques in biotechnology has plummeted in the past decade, even while capabilities have greatly increased. A graduate student with $20,000 can accomplish in a few months what would have required a full laboratory, years, and tens of millions of dollars in the 1990s. All of the much-lamented great expense in modern medicine lies in clinical translation, the long and drawn out process of trials, retrials, marketing, and manufacturing that is required to bring a laboratory proof of concept into clinics as a widely available therapy.

The SENS Research Foundation is focused on early stage research, following a plan that leads to technology demonstrations in the laboratory. With a proof of concept rejuvenation therapy the world will beat a path to their doorstep in order to fund clinical translation. The real challenge is here and now, raising the funds to get to that step. A few tens of thousands of dollars means the difference between a significant project delayed indefinitely or that project completed.

To pick one example, last year the community raised $20,000 to fund cutting edge work in allotopic expression of mitochondrial genes, a potential cure for the issue of mitochondrial damage in aging. That was enough to have a skilled young researcher work on the process for two of the thirteen genes of interest over a period of months. It really is that cheap given an existing group like the SENS Research Foundation with diverse connections and access to established laboratories.

Your donations make a real difference.

Spread the Word, Tell Your Friends

Don’t forget to tell your friends about this fundraiser. Talk to your community, online and offline. Consider running local events to help meet our goal of raising $50,000 from a grassroots community of supporters. The more people who know about the prospects for near future therapies resulting from rejuvenation research of the sort carried out by the SENS Research Foundation, the easier it becomes to raise funds and obtain institutional support for these research programs in the future.

Launched at /r/Futurology and in Conjunction with Longevity Day

Take a look at the generous spirit displayed at /r/Futurology, the futurist Reddit community, when given the chance to help. Scores of people there have already donated modest sums to the cause in response to our fundraiser: many thanks to you all!

The 1st of October marks the launch of this fundraiser, but it is also the International Day of Older Persons, and the International Longevity Alliance would like this to become an official Longevity Day. This year, just like last year, groups of futurists around the world will be holding events to mark the occasion, and this includes the scientists and advocates present at the 2014 Eurosymposium on Healthy Aging.

Download the 2014 Fundraiser Posters

The full size graphics here are large enough for 24 x 36 inch posters, but are also suitable for page-sized fliers. The original Photoshop files are available on request, but are a little large to put up here. Make as much use of these as you like – please help to spread the word and help this fundraiser to meet its target.

Color design, 3600 x 5600 pixels suitable for 24 x 36 inch posters, 11.3MB
Color design, 2400 x 3600 pixels suitable for letter size, 6.3MB

Blue design, 7200 x 10800 pixels suitable for 24 x 36 inch posters, 13.1MB
Blue design, 2400 x 3600 pixels suitable for letter size, 3.8MB

Reason is the founder of The Longevity Meme (now Fight Aging!). He saw the need for The Longevity Meme in late 2000, after spending a number of years searching for the most useful contribution he could make to the future of healthy life extension. When not advancing the Longevity Meme or Fight Aging!, Reason works as a technologist in a variety of industries. 
***

This work is reproduced here in accord with a Creative Commons Attribution license. It was originally published on FightAging.org.

Our Cells Will Be Guided and Protected by Machines – Article by Reason

Our Cells Will Be Guided and Protected by Machines – Article by Reason

The New Renaissance Hat
Reason
September 21, 2014
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A gulf presently lies between the nanoscale engineering of materials science on the one hand and the manipulation and understanding of evolved biological machinery on the other. In time that gulf will close: future industries will be capable of producing and controlling entirely artificial machines that integrate with, enhance, or replace our natural biological machines. Meanwhile biologists will be manufacturing ever more artificial and enhanced versions of cellular components, finding ways to make them better: evolution has rarely produced the best design possible for any given circumstance. Both sides will work towards one another and eventually meet in the middle.

Insofar as aging goes, a process of accumulating damage and malfunction in our biology, it is likely that this will first be successfully addressed and brought under medical control by producing various clearly envisaged ways to repair and maintain our cells just as they are: remove the damage, restore youthful function, and repeat as necessary. We stand much closer to that goal than the far more ambitious undertaking of building a better, more resilient, more easily repaired cell – a biology 2.0 if you like. That will happen, however. Our near descendants will be as much artificial as natural, and more capable and healthier for it.

The introduction of machinery to form a new human biology won’t happen all at once, however, and it isn’t entirely a far future prospect. There will be early gains and prototypes, the insertion of simpler types of machine into our cells for specific narrow purposes: sequestering specific proteins or wastes, or as drug factories to produce a compound in response to circumstances, or any one of a number of other similar tasks. If you want to consider nanoparticles or engineered assemblies of proteins capable of simple decision tree operations as machines then this has already happened in the lab:

Researchers Make Important Step Towards Creating Medical Nanorobots

Quote:

Researchers [have] have made an important step towards creating medical nanorobots. They discovered a way of enabling nano- and microparticles to produce logical calculations using a variety of biochemical reactions. Many scientists believe logical operations inside cells or in artificial biomolecular systems to be a way of controlling biological processes and creating full-fledged micro-and nano-robots, which can, for example, deliver drugs on schedule to those tissues where they are needed.

Further, there is a whole branch of cell research that involves finding ways to safely introduce ever larger objects into living cells, such as micrometer-scale constructs. In an age in which the state of the art for engineering computational devices is the creation of 14 nanometer features, there is a lot that might be accomplished in the years ahead with the space contained within a 1000 nanometer diameter sphere.

Introducing Micrometer-Sized Artificial Objects into Live Cells: A Method for Cell-Giant Unilamellar Vesicle Electrofusion

Quote:

Direct introduction of functional objects into living cells is a major topic in biology, medicine, and engineering studies, since such techniques facilitate manipulation of cells and allows one to change their functional properties arbitrarily. In order to introduce various objects into cells, several methods have been developed, for example, endocytosis and macropinocytosis. Nonetheless, the sizes of introducible objects are largely limited: up to several hundred nanometers and a few micrometers in diameter. In addition, the uptake of objects is dependent on cell type, and neither endocytosis nor macropinocytosis occur, for example, in lymphocytes. Even after successful endocytosis, incorporated objects are transported to the endosomes; they are then eventually transferred to the lysosome, in which acidic hydrolases degrade the materials. Hence, these two systems are not particularly suitable for introduction of functionally active molecules and objects.To overcome these obstacles, novel delivery systems have been contrived, such as cationic liposomes and nanomicelles, that are used for gene transfer; yet, only nucleic acids that are limited to a few hundred nanometers in size can be introduced. By employing peptide vectors, comparatively larger materials can be introduced into cells, although the size limit of peptides and beads is approximately 50nm, which is again insufficient for delivery of objects, such as DNA origami and larger functional beads.

Here, we report a method for introducing large objects of up to a micrometer in diameter into cultured mammalian cells by electrofusion of giant unilamellar vesicles (GUVs). We prepared GUVs containing various artificial objects using a water-in-oil emulsion centrifugation method. GUVs and dispersed HeLa cells were exposed to an alternating current (AC) field to induce a linear cell-GUV alignment, and then a direct current (DC) pulse was applied to facilitate transient electrofusion.

With uniformly sized fluorescent beads as size indexes, we successfully and efficiently introduced beads of 1 µm in diameter into living cells along with a plasmid mammalian expression vector. Our electrofusion did not affect cell viability. After the electrofusion, cells proliferated normally until confluence was reached, and the introduced fluorescent beads were inherited during cell division. Analysis by both confocal microscopy and flow cytometry supported these findings. As an alternative approach, we also introduced a designed nanostructure (DNA origami) into live cells. The results we report here represent a milestone for designing artificial symbiosis of functionally active objects (such as micro-machines) in living cells. Moreover, our technique can be used for drug delivery, tissue engineering, and cell manipulation.

Cell machinery will be a burgeoning medical industry of the 2030s, I imagine. To my eyes the greatest challenge in all of this is less the mass production of useful machines per se, and more the coordination and control of a body full of tens of trillions of such machines, perhaps from varied manufacturers, introduced for different goals, and over timescales long in comparison to business cycles and technological progress. That isn’t insurmountable, but it sounds like a much harder problem than those inherent in designing these machines and demonstrating them to be useful in cell cultures. It is a challenge on a scale of complexity that exceeds that of managing our present global communications network by many orders of magnitude. If you’ve been wondering what exactly it is we’ll be doing with the vast computational power available to us in the decades ahead, given that this metric continues to double every 18 months or so, here is one candidate.

Reason is the founder of The Longevity Meme (now Fight Aging!). He saw the need for The Longevity Meme in late 2000, after spending a number of years searching for the most useful contribution he could make to the future of healthy life extension. When not advancing the Longevity Meme or Fight Aging!, Reason works as a technologist in a variety of industries. 
***

This work is reproduced here in accord with a Creative Commons Attribution license. It was originally published on FightAging.org.

Dawn of the New Renaissance, Op. 21 (2003) – Musical Composition and Video by G. Stolyarov II

Dawn of the New Renaissance, Op. 21 (2003) – Musical Composition and Video by G. Stolyarov II

The New Renaissance Hat
G. Stolyarov II
September 20, 2014
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Mr. Stolyarov composed this work in 2003 in an effort to herald the beginning of a new era – the return to harmony, melody, meter, and heroic grandeur, the revival of an upright, luminous vision of human potential.

This work was remastered using the SynthFont2 software, with the Evanescence 2 and GMR Basico 1.1 instrument packs.

Download the MP3 file of this composition here.

See the index of Mr. Stolyarov’s compositions, all available for free download, here.

The artwork is Mr. Stolyarov’s Abstract Orderism Fractal 61, available for download here and here.

Remember to LIKE, FAVORITE, and SHARE this video in order to spread rational high culture to others.
Minuet #3 (Systematic Minuet), Op. 34 (2004) – Musical Composition and Video by G. Stolyarov II

Minuet #3 (Systematic Minuet), Op. 34 (2004) – Musical Composition and Video by G. Stolyarov II

The New Renaissance Hat
G. Stolyarov II
September 18, 2014
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This minuet for piano, composed by Mr. Stolyarov in 2004, conveys intricacy through directed melodies within a rigorously logical structure.

This work was remastered using the SynthFont2 software, with the Evanescence 2 and GMR Basico 1.1 instrument packs.

Download the MP3 file of this composition here.

See the index of Mr. Stolyarov’s compositions, all available for free download, here.

The artwork is Mr. Stolyarov’s Cube of Cubes, available for download here and here.

Remember to LIKE, FAVORITE, and SHARE this video in order to spread rational high culture to others.

Review of “The Transhumanist Wager” by Zoltan Istvan – Article by Kyrel Zantonavitch

Review of “The Transhumanist Wager” by Zoltan Istvan – Article by Kyrel Zantonavitch

The New Renaissance Hat
Kyrel Zantonavitch
August 20, 2014
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The Transhumanist Wager by Zoltan Istvan is available on Amazon in paperback and Kindle formats.

***

This is the best novel I’ve read in over 30 years! I don’t ever expect to see its like again. Fascinating, amazing, and shocking to the point of numbness.

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It’s rather comparable to Atlas Shrugged — the earth-shaking epic and classic by Ayn Rand from 1957. It has Atlas Shrugged’s magisterial story sweep and stunning philosophical ambition. It has Rand’s quasi-god-like heroism too. And like the other novel, Zoltan Istvan’s book is looking to mercilessly conquer the world.

***

Let’s hope!

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Mr. Istvan’s thunderous 300-page saga, The Transhumanist Wager, is a truly remarkable novel of ideas. It’s unique. It has no peers or rivals. And it’s completely unexpected and unprecedented.

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Like Atlas Shrugged, it offers many formidable intellectual challenges. One or two of these I’ve yet to work out. Like Rand’s lengthy magnum opus, The Transhumanist Wager is mesmerizingly philosophically bold and rich. And like Atlas, it’s rather repetitive in introducing these dynamic, new ideas to a silently dumbfounded world. But at least you clearly know where each novelist-philosopher stands on the issues, and what controversial and ferocious thing they each have to teach us.

***

I find this to be an unapologetically extreme and revolutionary book. A true tour de force and deep-thinking book which comes at all of us from out of the blue. If you don’t read it, you’re fatuously and tragically missing out. Wager is a historical game-changer, and likely to spark a new era in mankind’s evolution. Humans will never be the same.

***

It seems a shame and crime to give away virtually anything in the plot, so I’ll keep it very light. The hero of the story seeks a truly astounding level of personal growth and, simultaneously, human evolutionary ascent. He effectively threatens to dethrone Zeus himself. Whether Jethro Knights — the alter ego of Zoltan Istvan – actually achieves this is something the high-intelligence, high-virtue reader will have to find out for himself.

***

This book is jaw-droppingly ambitious and powerful. It’s also massively persuasive. The novel is filled with energy, zealotry, ferocity, honesty, courage, and heedless impetuosity. A visionary and fundamentalist book of gigantic and fearless integrity which is almost utterly loyal to its own monumental and yet somewhat narrow beliefs. But make no mistake: these ideas and beliefs are world-rocking.

***

Ultimately, Mr. Istvan is a slightly but significantly limited philosopher. He’s not an Objectivist, and isn’t that familiar with Ayn Rand’s intellectual beliefs and theories, evidently. Still, I consider Zoltan Istvan to be an immensely powerful neoliberal thinker and a formidable cultural warrior. He fights for the Good Guys; and he aims to capture a great deal of the future. Amazingly, Mr. Istvan may have come to these ultra-high-level theories and points of view without having had much help from today’s leading neoliberals: the economic Austrians, the political libertarians, and the philosophical Objectivists. Maybe Zoltan Istvan just used his own exceptionally high virtue and Herculean fearlessness to derive his “transhumanist” philosophy from the classics of human literature and intellectualism, especially the Greeks, Romans, Renaissance, and Enlightenment thinkers. Astonishing, if true!

***

And yet…Mr. Istvan isn’t that strong a neoliberal. He, his hero, and this novel don’t entirely believe in the epistemology of reason, the ethics of individualism, and the politics of liberty.

***

Still, what a dynamo and hero this Zoltan character is! What a vivacious, ferocious, and catastrophic cultural warrior! Mr. Istvan is a one-man wrecking crew of contemporary culture and evidently a magnificent being of immense and singular stature. Or at least his alter ego in the story is.

***

Altho’ the ideas inside somewhat overwhelm it, The Transhumanist Wager is a genuine novel which tells a dramatic, wonderous, and wide-ranging tale. The plot is exciting, involving, and enthralling. The characters are generally believable, often archetypal, and sometimes indelible. This is a heroic epic which transverses the entire planet and overwhelmingly impacts all of mankind.

***

I also found this book to be a hugely enjoyable, winding, and suspenseful yarn. It’s great fun to read, and even more fun to think about.

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Overall I consider Zoltan Istvan’s The Transhumanist Wager to be outstanding as a novel, and even better as a book of theoretical and practical philosophy, regarding the shooting-star ascent of man, and our soon-to-be superhuman future.

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Kyrel Zantonavitch is the founder of The Liberal Institute  (http://www.liberalinstitute.com/) and a writer for Rebirth of Reason (http://www.rebirthofreason.com). He can be contacted at zantonavitch@gmail.com.